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4bva

From Proteopedia

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'''Unreleased structure'''
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{{STRUCTURE_4bva| PDB=4bva | SCENE= }}
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===Cristal structure of the NADPH-T3 form of mouse Mu-crystallin.===
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{{ABSTRACT_PUBMED_24467707}}
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The entry 4bva is ON HOLD until Paper Publication
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==Function==
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[[http://www.uniprot.org/uniprot/CRYM_MOUSE CRYM_MOUSE]] Specifically catalyzes the reduction of imine bonds in brain substrates that may include cystathionine ketimine (CysK) and lanthionine ketimine (LK). Binds thyroid hormone which is a strong reversible inhibitor. Presumably involved in the regulation of the free intracellular concentration of triiodothyronine and access to its nuclear receptors (By similarity).
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Authors: Borel, F., Hachi, I., Palencia, A., Gaillard, M.C., Ferrer, J.L.
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==About this Structure==
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[[4bva]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BVA OCA].
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Description: Cristal structure of the NADPH-T3 form of mouse Mu-crystallin.
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==Reference==
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<ref group="xtra">PMID:024467707</ref><references group="xtra"/><references/>
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[[Category: Thiomorpholine-carboxylate dehydrogenase]]
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[[Category: Borel, F.]]
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[[Category: Ferrer, J L.]]
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[[Category: Gaillard, M C.]]
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[[Category: Hachi, I.]]
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[[Category: Palencia, A.]]
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[[Category: Oxidoreductase]]

Revision as of 11:11, 5 February 2014

Template:STRUCTURE 4bva

Contents

Cristal structure of the NADPH-T3 form of mouse Mu-crystallin.

Template:ABSTRACT PUBMED 24467707

Function

[CRYM_MOUSE] Specifically catalyzes the reduction of imine bonds in brain substrates that may include cystathionine ketimine (CysK) and lanthionine ketimine (LK). Binds thyroid hormone which is a strong reversible inhibitor. Presumably involved in the regulation of the free intracellular concentration of triiodothyronine and access to its nuclear receptors (By similarity).

About this Structure

4bva is a 2 chain structure. Full crystallographic information is available from OCA.

Reference

  • Borel F, Hachi I, Palencia A, Gaillard MC, Ferrer JL. Crystal Structure of mouse Mu-crystallin complexed with NADPH and the T3 thyroid hormone. FEBS J. 2014 Jan 27. doi: 10.1111/febs.12726. PMID:24467707 doi:http://dx.doi.org/10.1111/febs.12726

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