4bv9
From Proteopedia
(Difference between revisions)
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- | + | {{STRUCTURE_4bv9| PDB=4bv9 | SCENE= }} | |
+ | ===Crystal structure of the NADPH form of mouse Mu-crystallin.=== | ||
+ | {{ABSTRACT_PUBMED_24467707}} | ||
- | + | ==Function== | |
+ | [[http://www.uniprot.org/uniprot/CRYM_MOUSE CRYM_MOUSE]] Specifically catalyzes the reduction of imine bonds in brain substrates that may include cystathionine ketimine (CysK) and lanthionine ketimine (LK). Binds thyroid hormone which is a strong reversible inhibitor. Presumably involved in the regulation of the free intracellular concentration of triiodothyronine and access to its nuclear receptors (By similarity). | ||
- | + | ==About this Structure== | |
+ | [[4bv9]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BV9 OCA]. | ||
- | + | ==Reference== | |
+ | <ref group="xtra">PMID:024467707</ref><references group="xtra"/><references/> | ||
+ | [[Category: Thiomorpholine-carboxylate dehydrogenase]] | ||
+ | [[Category: Borel, F.]] | ||
+ | [[Category: Ferrer, J L.]] | ||
+ | [[Category: Gaillard, M C.]] | ||
+ | [[Category: Hachi, I.]] | ||
+ | [[Category: Palencia, A.]] | ||
+ | [[Category: Oxidoreductase]] |
Revision as of 11:14, 5 February 2014
Contents |
Crystal structure of the NADPH form of mouse Mu-crystallin.
Template:ABSTRACT PUBMED 24467707
Function
[CRYM_MOUSE] Specifically catalyzes the reduction of imine bonds in brain substrates that may include cystathionine ketimine (CysK) and lanthionine ketimine (LK). Binds thyroid hormone which is a strong reversible inhibitor. Presumably involved in the regulation of the free intracellular concentration of triiodothyronine and access to its nuclear receptors (By similarity).
About this Structure
4bv9 is a 2 chain structure. Full crystallographic information is available from OCA.
Reference
- Borel F, Hachi I, Palencia A, Gaillard MC, Ferrer JL. Crystal Structure of mouse Mu-crystallin complexed with NADPH and the T3 thyroid hormone. FEBS J. 2014 Jan 27. doi: 10.1111/febs.12726. PMID:24467707 doi:http://dx.doi.org/10.1111/febs.12726