3zj8

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m (Protected "3zj8" [edit=sysop:move=sysop])
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'''Unreleased structure'''
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{{STRUCTURE_3zj8| PDB=3zj8 | SCENE= }}
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===Crystal structure of strictosidine glucosidase in complex with inhibitor-2===
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The entry 3zj8 is ON HOLD until Paper Publication
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==Function==
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[[http://www.uniprot.org/uniprot/SG1_RAUSE SG1_RAUSE]] Glucosidase specifically involved in alkaloid biosynthesis leading to the accumulation of several alkaloids, including ajmaline, an important plant-derived pharmaceutical used in the therapy of heart disorders.<ref>PMID:22004291</ref>
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Authors: Xia, L., Lin, H., Panjikar, S., Ruppert, M., Castiglia, A., Rajendran, C., Wang, M., Schuebel, H., Warzecha, H., Jaeger, V., Stoeckigt, J.
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==About this Structure==
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[[3zj8]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZJ8 OCA].
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Description: Crystal structure of strictosidine glucosidase in complex with inhibitor-2
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==Reference==
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<references group="xtra"/><references/>
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[[Category: Castiglia, A.]]
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[[Category: Jaeger, V.]]
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[[Category: Lin, H.]]
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[[Category: Panjikar, S.]]
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[[Category: Rajendran, C.]]
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[[Category: Ruppert, M.]]
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[[Category: Schuebel, H.]]
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[[Category: Stoeckigt, J.]]
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[[Category: Wang, M.]]
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[[Category: Warzecha, H.]]
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[[Category: Xia, L.]]
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[[Category: Alkaloid]]
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[[Category: Hydrolase]]
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[[Category: Inhibitor]]

Revision as of 11:28, 5 February 2014

Template:STRUCTURE 3zj8

Contents

Crystal structure of strictosidine glucosidase in complex with inhibitor-2

Function

[SG1_RAUSE] Glucosidase specifically involved in alkaloid biosynthesis leading to the accumulation of several alkaloids, including ajmaline, an important plant-derived pharmaceutical used in the therapy of heart disorders.[1]

About this Structure

3zj8 is a 2 chain structure. Full crystallographic information is available from OCA.

Reference

  1. ↑ Xia L, Ruppert M, Wang M, Panjikar S, Lin H, Rajendran C, Barleben L, Stockigt J. Structures of Alkaloid Biosynthetic Glucosidases Decode Substrate Specificity. ACS Chem Biol. 2011 Oct 28. PMID:22004291 doi:10.1021/cb200267w

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