4nfn
From Proteopedia
(Difference between revisions)
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| - | + | {{STRUCTURE_4nfn| PDB=4nfn | SCENE= }} | |
| + | ===Human tau tubulin kinase 1 (TTBK1) complexed with 3-({5-[(4-amino-4-methylpiperidin-1-yl)methyl]pyrrolo[2,1-f][1,2,4]triazin-4-yl}amino)-5-bromophenol=== | ||
| - | + | ==Function== | |
| + | [[http://www.uniprot.org/uniprot/TTBK1_HUMAN TTBK1_HUMAN]] Serine/threonine kinase which is able to phosphorylate TAU on serine, threonine and tyrosine residues. Induces aggregation of TAU.<ref>PMID:16923168</ref> | ||
| - | + | ==About this Structure== | |
| + | [[4nfn]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NFN OCA]. | ||
| - | + | ==Reference== | |
| + | <references group="xtra"/><references/> | ||
| + | [[Category: Non-specific serine/threonine protein kinase]] | ||
| + | [[Category: Sheriff, S.]] | ||
| + | [[Category: Phosphotransferase]] | ||
| + | [[Category: Protein kinase]] | ||
| + | [[Category: Transferase-transferase inhibitor complex]] | ||
Revision as of 11:37, 5 February 2014
Contents |
Human tau tubulin kinase 1 (TTBK1) complexed with 3-({5-[(4-amino-4-methylpiperidin-1-yl)methyl]pyrrolo[2,1-f][1,2,4]triazin-4-yl}amino)-5-bromophenol
Function
[TTBK1_HUMAN] Serine/threonine kinase which is able to phosphorylate TAU on serine, threonine and tyrosine residues. Induces aggregation of TAU.[1]
About this Structure
4nfn is a 1 chain structure. Full crystallographic information is available from OCA.
