3kko

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[[Image:3kko.jpg|left|200px]]
 
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{{STRUCTURE_3kko| PDB=3kko | SCENE= }}
{{STRUCTURE_3kko| PDB=3kko | SCENE= }}
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===Crystal structure of M-Ras P40D/D41E/L51R in complex with GppNHp===
===Crystal structure of M-Ras P40D/D41E/L51R in complex with GppNHp===
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{{ABSTRACT_PUBMED_20479006}}
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==Function==
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[[http://www.uniprot.org/uniprot/RASM_MOUSE RASM_MOUSE]] May serve as an important signal transducer for a novel upstream stimuli in controlling cell proliferation. Weakly activates the MAP kinase pathway (By similarity).
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{{ABSTRACT_PUBMED_20479006}}
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==About this Structure==
==About this Structure==
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3KKO is a 3 chains structure with sequences from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KKO OCA].
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[[3kko]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KKO OCA].
==Reference==
==Reference==
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<ref group="xtra">PMID:20479006</ref><references group="xtra"/>
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<ref group="xtra">PMID:020479006</ref><references group="xtra"/><references/>
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[[Category: Mus musculus]]
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[[Category: Lk3 transgenic mice]]
[[Category: Ijiri, Y.]]
[[Category: Ijiri, Y.]]
[[Category: Inoue, T.]]
[[Category: Inoue, T.]]
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[[Category: Gtpase]]
[[Category: Gtpase]]
[[Category: Signaling protein]]
[[Category: Signaling protein]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jun 16 08:39:22 2010''
 

Revision as of 03:23, 13 February 2014

Template:STRUCTURE 3kko

Contents

Crystal structure of M-Ras P40D/D41E/L51R in complex with GppNHp

Template:ABSTRACT PUBMED 20479006

Function

[RASM_MOUSE] May serve as an important signal transducer for a novel upstream stimuli in controlling cell proliferation. Weakly activates the MAP kinase pathway (By similarity).

About this Structure

3kko is a 3 chain structure with sequence from Lk3 transgenic mice. Full crystallographic information is available from OCA.

Reference

  • Shima F, Ijiri Y, Muraoka S, Liao J, Ye M, Araki M, Matsumoto K, Yamamoto N, Sugimoto T, Yoshikawa Y, Kumasaka T, Yamamoto M, Tamura A, Kataoka T. Structural basis for conformational dynamics of GTP-bound Ras protein. J Biol Chem. 2010 Jul 16;285(29):22696-705. Epub 2010 May 17. PMID:20479006 doi:10.1074/jbc.M110.125161

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OCA

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