3lja

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[[Image:3lja.png|left|200px]]
 
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{{STRUCTURE_3lja| PDB=3lja | SCENE= }}
{{STRUCTURE_3lja| PDB=3lja | SCENE= }}
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===Using Soft X-Rays for a Detailed Picture of Divalent Metal Binding in the Nucleosome===
===Using Soft X-Rays for a Detailed Picture of Divalent Metal Binding in the Nucleosome===
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{{ABSTRACT_PUBMED_20350553}}
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{{ABSTRACT_PUBMED_20350553}}
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==Function==
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[[http://www.uniprot.org/uniprot/H2B11_XENLA H2B11_XENLA]] Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. [[http://www.uniprot.org/uniprot/H32_XENLA H32_XENLA]] Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. [[http://www.uniprot.org/uniprot/H4_XENLA H4_XENLA]] Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
==About this Structure==
==About this Structure==
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[[3lja]] is a 10 chain structure with sequence from [http://en.wikipedia.org/wiki/Xenopus_laevis Xenopus laevis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LJA OCA].
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[[3lja]] is a 10 chain structure with sequence from [http://en.wikipedia.org/wiki/African_clawed_frog African clawed frog]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LJA OCA].
==See Also==
==See Also==
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==Reference==
==Reference==
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<ref group="xtra">PMID:020350553</ref><references group="xtra"/>
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<ref group="xtra">PMID:020350553</ref><references group="xtra"/><references/>
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[[Category: Xenopus laevis]]
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[[Category: African clawed frog]]
[[Category: Davey, C A.]]
[[Category: Davey, C A.]]
[[Category: Wu, B.]]
[[Category: Wu, B.]]

Revision as of 03:28, 13 February 2014

Template:STRUCTURE 3lja

Contents

Using Soft X-Rays for a Detailed Picture of Divalent Metal Binding in the Nucleosome

Template:ABSTRACT PUBMED 20350553

Function

[H2B11_XENLA] Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. [H32_XENLA] Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. [H4_XENLA] Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

About this Structure

3lja is a 10 chain structure with sequence from African clawed frog. Full crystallographic information is available from OCA.

See Also

Reference

  • Wu B, Davey CA. Using soft X-rays for a detailed picture of divalent metal binding in the nucleosome. J Mol Biol. 2010 May 21;398(5):633-40. Epub 2010 Mar 27. PMID:20350553 doi:10.1016/j.jmb.2010.03.038

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