4lj3

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{{STRUCTURE_4lj3| PDB=4lj3 | SCENE= }}
{{STRUCTURE_4lj3| PDB=4lj3 | SCENE= }}
===Crystal structure of the EAL domain of c-di-GMP specific phosphodiesterase YahA in complex with substrate c-di-GMP and Ca++===
===Crystal structure of the EAL domain of c-di-GMP specific phosphodiesterase YahA in complex with substrate c-di-GMP and Ca++===
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{{ABSTRACT_PUBMED_24451384}}
==Function==
==Function==
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==About this Structure==
==About this Structure==
[[4lj3]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LJ3 OCA].
[[4lj3]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LJ3 OCA].
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==Reference==
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<ref group="xtra">PMID:024451384</ref><references group="xtra"/><references/>
[[Category: Schirmer, T.]]
[[Category: Schirmer, T.]]
[[Category: Sundriyal, A.]]
[[Category: Sundriyal, A.]]

Revision as of 03:40, 13 February 2014

Template:STRUCTURE 4lj3

Contents

Crystal structure of the EAL domain of c-di-GMP specific phosphodiesterase YahA in complex with substrate c-di-GMP and Ca++

Template:ABSTRACT PUBMED 24451384

Function

[YAHA_ECOLI] Hydrolyzes c-di-GMP (cyclic bis(3'-5') dimeric GMP) to 5'-pGpG, known as PDE-A activity. PDE-B activity, that is hydrolysis of 5'-pGpG to GMP, proceeds only very slowly.

About this Structure

4lj3 is a 2 chain structure. Full crystallographic information is available from OCA.

Reference

  • Sundriyal A, Massa C, Samoray D, Zehender F, Sharpe T, Jenal U, Schirmer T. Inherent regulation of EAL domain-catalyzed hydrolysis of second messenger c-di-GMP. J Biol Chem. 2014 Jan 22. PMID:24451384 doi:http://dx.doi.org/10.1074/jbc.M113.516195

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