4lsd

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==About this Structure==
==About this Structure==
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[[4lsd]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LSD OCA].
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[[4lsd]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LSD OCA].
==Reference==
==Reference==
<ref group="xtra">PMID:024114836</ref><references group="xtra"/><references/>
<ref group="xtra">PMID:024114836</ref><references group="xtra"/><references/>
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[[Category: Homo sapiens]]
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[[Category: Human]]
[[Category: Chinnam, N.]]
[[Category: Chinnam, N.]]
[[Category: Erickson, H.]]
[[Category: Erickson, H.]]

Revision as of 04:07, 13 February 2014

Template:STRUCTURE 4lsd

Contents

Myokine structure

Template:ABSTRACT PUBMED 24114836

Function

[FNDC5_HUMAN] Irisin: mediates beneficial effects of muscular exercise. Induces browning of white adipose tissue by stimulating UCP1 expression, at least in part, via the nuclear receptor PPARA (By similarity).

About this Structure

4lsd is a 8 chain structure with sequence from Human. Full crystallographic information is available from OCA.

Reference

  • Schumacher MA, Chinnam N, Ohashi T, Shah RS, Erickson H. Structure of irisin reveals a novel intersubunit beta-sheet fibronectin (FNIII) dimer; implications for receptor activation. J Biol Chem. 2013 Oct 10. PMID:24114836 doi:http://dx.doi.org/10.1074/jbc.M113.516641

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