4mxi
From Proteopedia
(Difference between revisions)
| Line 7: | Line 7: | ||
==About this Structure== | ==About this Structure== | ||
| - | [[4mxi]] is a 7 chain structure with sequence from [http://en.wikipedia.org/wiki/ | + | [[4mxi]] is a 7 chain structure with sequence from [http://en.wikipedia.org/wiki/Staa8 Staa8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MXI OCA]. |
==Reference== | ==Reference== | ||
<ref group="xtra">PMID:024106749</ref><references group="xtra"/><references/> | <ref group="xtra">PMID:024106749</ref><references group="xtra"/><references/> | ||
[[Category: Endopeptidase Clp]] | [[Category: Endopeptidase Clp]] | ||
| - | [[Category: | + | [[Category: Staa8]] |
[[Category: Alte, F.]] | [[Category: Alte, F.]] | ||
[[Category: Gersch, M.]] | [[Category: Gersch, M.]] | ||
Revision as of 04:34, 13 February 2014
Contents |
ClpP Ser98dhA
Template:ABSTRACT PUBMED 24106749
Function
[CLPP_STAA8] Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity).
About this Structure
4mxi is a 7 chain structure with sequence from Staa8. Full crystallographic information is available from OCA.
Reference
- Gersch M, Kolb R, Alte F, Groll M, Sieber SA. Disruption of oligomerization and dehydroalanine formation as mechanisms for ClpP protease inhibition. J Am Chem Soc. 2013 Oct 9. PMID:24106749 doi:http://dx.doi.org/10.1021/ja4082793
Categories: Endopeptidase Clp | Staa8 | Alte, F. | Gersch, M. | Groll, M. | Kolb, R. | Sieber, S A. | Clpp | Complex disassembly | Dehydroalanine | Hydrolase | Inhibition | Serine protease
