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2mdq

From Proteopedia

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'''Unreleased structure'''
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{{STRUCTURE_2mdq| PDB=2mdq | SCENE= }}
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===A Novel 4/7-Conotoxin LvIA from Conus lividus that Selectively Blocks 3 2 vs. 6/3 2 3 Nicotinic Acetylcholine Receptors===
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{{ABSTRACT_PUBMED_24398291}}
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The entry 2mdq is ON HOLD until Paper Publication
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==Function==
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[[http://www.uniprot.org/uniprot/L8BU87_CONLI L8BU87_CONLI]] Alpha-conotoxins act on postsynaptic membranes, they bind to the nicotinic acetylcholine receptors (nAChR) and thus inhibit them (By similarity).[RuleBase:RU004345]
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Authors: Schroeder, C.I.
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==About this Structure==
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[[2mdq]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MDQ OCA].
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Description: A Novel 4/7-Conotoxin LvIA from Conus lividus that Selectively Blocks 3 2 vs. 6/3 2 3 Nicotinic Acetylcholine Receptors
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==Reference==
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<ref group="xtra">PMID:024398291</ref><references group="xtra"/><references/>
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[[Category: Schroeder, C I.]]
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[[Category: Alfa-conotoxin]]
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[[Category: Conotoxin]]
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[[Category: Disulfide rich]]
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[[Category: Nicotinic acetylcholine receptor]]
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[[Category: Toxin]]

Revision as of 05:06, 13 February 2014

Template:STRUCTURE 2mdq

Contents

A Novel 4/7-Conotoxin LvIA from Conus lividus that Selectively Blocks 3 2 vs. 6/3 2 3 Nicotinic Acetylcholine Receptors

Template:ABSTRACT PUBMED 24398291

Function

[L8BU87_CONLI] Alpha-conotoxins act on postsynaptic membranes, they bind to the nicotinic acetylcholine receptors (nAChR) and thus inhibit them (By similarity).[RuleBase:RU004345]

About this Structure

2mdq is a 1 chain structure. Full experimental information is available from OCA.

Reference

  • Luo S, Zhangsun D, Schroeder CI, Zhu X, Hu Y, Wu Y, Weltzin MM, Eberhard S, Kaas Q, Craik DJ, McIntosh JM, Whiteaker P. A novel alpha4/7-conotoxin LvIA from Conus lividus that selectively blocks alpha3beta2 vs. alpha6/alpha3beta2beta3 nicotinic acetylcholine receptors. FASEB J. 2014 Jan 7. PMID:24398291 doi:http://dx.doi.org/10.1096/fj.13-244103

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OCA

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