4cd3

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m (Protected "4cd3" [edit=sysop:move=sysop])
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'''Unreleased structure'''
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{{STRUCTURE_4cd3| PDB=4cd3 | SCENE= }}
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===RnNTPDase2 X4 variant in complex with PSB-071===
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{{ABSTRACT_PUBMED_24462745}}
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The entry 4cd3 is ON HOLD
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==Function==
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[[http://www.uniprot.org/uniprot/ENTP2_RAT ENTP2_RAT]] In the nervous system, could hydrolyze ATP and other nucleotides to regulate purinergic neurotransmission. Hydrolyzes ADP only to a marginal extent.
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Authors: Zebisch, M., Schaefer, P., Straeter, N.
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==About this Structure==
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[[4cd3]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CD3 OCA].
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Description: RnNTPDase2 X4 variant in complex with PSB-071
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==Reference==
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<ref group="xtra">PMID:024462745</ref><references group="xtra"/><references/>
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[[Category: Schaefer, P.]]
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[[Category: Straeter, N.]]
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[[Category: Zebisch, M.]]
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[[Category: Apyrase]]
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[[Category: Atpase]]
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[[Category: Drug design]]
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[[Category: Hydrolase]]
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[[Category: Inhibitor]]
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[[Category: Ntpdase]]
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[[Category: Purinergic signalling]]

Revision as of 05:10, 13 February 2014

Template:STRUCTURE 4cd3

Contents

RnNTPDase2 X4 variant in complex with PSB-071

Template:ABSTRACT PUBMED 24462745

Function

[ENTP2_RAT] In the nervous system, could hydrolyze ATP and other nucleotides to regulate purinergic neurotransmission. Hydrolyzes ADP only to a marginal extent.

About this Structure

4cd3 is a 1 chain structure. Full crystallographic information is available from OCA.

Reference

  • Zebisch M, Baqi Y, Schafer P, Muller CE, Strater N. Crystal structure of NTPDase2 in complex with the sulfoanthraquinone inhibitor PSB-071. J Struct Biol. 2014 Jan 21. pii: S1047-8477(14)00006-9. doi:, 10.1016/j.jsb.2014.01.005. PMID:24462745 doi:http://dx.doi.org/10.1016/j.jsb.2014.01.005

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OCA

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