4nyn

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
m (Protected "4nyn" [edit=sysop:move=sysop])
Line 1: Line 1:
-
'''Unreleased structure'''
+
{{STRUCTURE_4nyn| PDB=4nyn | SCENE= }}
 +
===Crystal structure of RNase H1 from halophilic archaeon Halobacterium salinarum NRC-1===
-
The entry 4nyn is ON HOLD
+
==Function==
 +
[[http://www.uniprot.org/uniprot/RNH_HALSA RNH_HALSA]] Nuclease that specifically degrades the RNA of RNA-DNA hybrids; seems to act exonucleolytically on RNA/DNA hybrids. Endonucleolytically removes RNA primers from the Okazaki fragments of lagging strand synthesis on its own. Complements the temperature-sensitive phenotype of an E.coli double rnhA/rnhB (RNase H) disruption mutant.<ref>PMID:15115438</ref>
-
Authors: You, D.J., Angkawidjaja, C., Koga, Y., Kanaya, S.
+
==About this Structure==
 +
[[4nyn]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NYN OCA].
-
Description: Crystal structure of RNase H1 from halophilic archaeon Halobacterium salinarum NRC-1
+
==Reference==
 +
<references group="xtra"/><references/>
 +
[[Category: Ribonuclease H]]
 +
[[Category: Angkawidjaja, C.]]
 +
[[Category: Kanaya, S.]]
 +
[[Category: Koga, Y.]]
 +
[[Category: You, D J.]]
 +
[[Category: Hydrolase]]
 +
[[Category: Rnase h1]]

Revision as of 05:24, 13 February 2014

Template:STRUCTURE 4nyn

Contents

Crystal structure of RNase H1 from halophilic archaeon Halobacterium salinarum NRC-1

Function

[RNH_HALSA] Nuclease that specifically degrades the RNA of RNA-DNA hybrids; seems to act exonucleolytically on RNA/DNA hybrids. Endonucleolytically removes RNA primers from the Okazaki fragments of lagging strand synthesis on its own. Complements the temperature-sensitive phenotype of an E.coli double rnhA/rnhB (RNase H) disruption mutant.[1]

About this Structure

4nyn is a 2 chain structure. Full crystallographic information is available from OCA.

Reference

  1. ↑ Ohtani N, Yanagawa H, Tomita M, Itaya M. Identification of the first archaeal Type 1 RNase H gene from Halobacterium sp. NRC-1: archaeal RNase HI can cleave an RNA-DNA junction. Biochem J. 2004 Aug 1;381(Pt 3):795-802. PMID:15115438 doi:http://dx.doi.org/10.1042/BJ20040153

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/4nyn"
Personal tools