2ivj

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{{STRUCTURE_2ivj| PDB=2ivj | SCENE= }}
{{STRUCTURE_2ivj| PDB=2ivj | SCENE= }}
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===ISOPENICILLIN N SYNTHASE FROM ASPERGILLUS NIDULANS (ANAEROBIC AC-CYCLOPROPYLGLYCINE FE COMPLEX)===
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===Isopenicillin N Synthase From Aspergillus Nidulans (Anaerobic Ac- cyclopropylglycine Fe Complex)===
{{ABSTRACT_PUBMED_17397141}}
{{ABSTRACT_PUBMED_17397141}}
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==Function==
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[[http://www.uniprot.org/uniprot/IPNS_EMENI IPNS_EMENI]] Removes, in the presence of oxygen, 4 hydrogen atoms from delta-L-(alpha-aminoadipyl)-L-cysteinyl-D-valine (ACV) to form the azetidinone and thiazolidine rings of isopenicillin.
==About this Structure==
==About this Structure==
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[[2ivj]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Emericella_nidulans Emericella nidulans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IVJ OCA].
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[[2ivj]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/A._nidulans A. nidulans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IVJ OCA].
==See Also==
==See Also==
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==Reference==
==Reference==
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<ref group="xtra">PMID:017397141</ref><ref group="xtra">PMID:010537113</ref><ref group="xtra">PMID:009194566</ref><references group="xtra"/>
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<ref group="xtra">PMID:017397141</ref><references group="xtra"/><references/>
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[[Category: Emericella nidulans]]
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[[Category: A. nidulans]]
[[Category: Isopenicillin-N synthase]]
[[Category: Isopenicillin-N synthase]]
[[Category: Adlington, R M.]]
[[Category: Adlington, R M.]]

Revision as of 14:26, 19 February 2014

Template:STRUCTURE 2ivj

Contents

Isopenicillin N Synthase From Aspergillus Nidulans (Anaerobic Ac- cyclopropylglycine Fe Complex)

Template:ABSTRACT PUBMED 17397141

Function

[IPNS_EMENI] Removes, in the presence of oxygen, 4 hydrogen atoms from delta-L-(alpha-aminoadipyl)-L-cysteinyl-D-valine (ACV) to form the azetidinone and thiazolidine rings of isopenicillin.

About this Structure

2ivj is a 1 chain structure with sequence from A. nidulans. Full crystallographic information is available from OCA.

See Also

Reference

  • Howard-Jones AR, Elkins JM, Clifton IJ, Roach PL, Adlington RM, Baldwin JE, Rutledge PJ. Interactions of isopenicillin N synthase with cyclopropyl-containing substrate analogues reveal new mechanistic insight. Biochemistry. 2007 Apr 24;46(16):4755-62. Epub 2007 Mar 31. PMID:17397141 doi:10.1021/bi062314q

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