4ldy

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==Reference==
==Reference==
<ref group="xtra">PMID:024485461</ref><references group="xtra"/><references/>
<ref group="xtra">PMID:024485461</ref><references group="xtra"/><references/>
 +
[[Category: Berg, W M.A van den.]]
[[Category: Boer, D R.]]
[[Category: Boer, D R.]]
[[Category: Coll, M.]]
[[Category: Coll, M.]]
 +
[[Category: Freire-Rios, A.]]
 +
[[Category: Weijers, D.]]
[[Category: Dna binding]]
[[Category: Dna binding]]
[[Category: Nucleus]]
[[Category: Nucleus]]
[[Category: Transcription]]
[[Category: Transcription]]
[[Category: Transcription factor]]
[[Category: Transcription factor]]

Revision as of 15:19, 19 February 2014

Template:STRUCTURE 4ldy

Contents

Crystal structure of the DNA binding domain of the G245A mutant of arabidopsis thaliana auxin reponse factor 1

Template:ABSTRACT PUBMED 24485461

Function

[ARFA_ARATH] Auxin response factors (ARFs) are transcriptional factors that binds specifically to the DNA sequence 5'-TGTCTC-3' found in the auxin-responsive promoter elements (AuxREs). Seems to act as transcriptional repressor. Formation of heterodimers with Aux/IAA proteins may alter their ability to modulate early auxin response genes expression. Promotes flowering, stamen development, floral organ abscission and fruit dehiscence. Acts as repressor of IAA2, IAA3 and IAA7.[1] [2]

About this Structure

4ldy is a 2 chain structure. Full crystallographic information is available from OCA.

Reference

  • Boer DR, Freire-Rios A, van den Berg WA, Saaki T, Manfield IW, Kepinski S, Lopez-Vidrieo I, Franco-Zorrilla JM, de Vries SC, Solano R, Weijers D, Coll M. Structural Basis for DNA Binding Specificity by the Auxin-Dependent ARF Transcription Factors. Cell. 2014 Jan 30;156(3):577-89. doi: 10.1016/j.cell.2013.12.027. PMID:24485461 doi:http://dx.doi.org/10.1016/j.cell.2013.12.027
  1. Hagen G, Guilfoyle T. Auxin-responsive gene expression: genes, promoters and regulatory factors. Plant Mol Biol. 2002 Jun-Jul;49(3-4):373-85. PMID:12036261
  2. Ellis CM, Nagpal P, Young JC, Hagen G, Guilfoyle TJ, Reed JW. AUXIN RESPONSE FACTOR1 and AUXIN RESPONSE FACTOR2 regulate senescence and floral organ abscission in Arabidopsis thaliana. Development. 2005 Oct;132(20):4563-74. Epub 2005 Sep 21. PMID:16176952 doi:http://dx.doi.org/dev.02012

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