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3onf
From Proteopedia
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{{STRUCTURE_3onf| PDB=3onf | SCENE= }} | {{STRUCTURE_3onf| PDB=3onf | SCENE= }} | ||
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===Crystal structure of Lupinus luteus S-adenosyl-L-homocysteine hydrolase in complex with cordycepin=== | ===Crystal structure of Lupinus luteus S-adenosyl-L-homocysteine hydrolase in complex with cordycepin=== | ||
| + | {{ABSTRACT_PUBMED_22349223}} | ||
| + | ==Function== | ||
| + | [[http://www.uniprot.org/uniprot/SAHH_LUPLU SAHH_LUPLU]] Adenosylhomocysteine is a competitive inhibitor of S-adenosyl-L-methionine-dependent methyl transferase reactions; therefore adenosylhomocysteinase may play a key role in the control of methylations via regulation of the intracellular concentration of adenosylhomocysteine (By similarity). | ||
| - | + | ==About this Structure== | |
| - | + | [[3onf]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/European_yellow_lupin European yellow lupin]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ONF OCA]. | |
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| - | == | + | ==See Also== |
| - | [[ | + | *[[S-adenosylhomocysteine hydrolase|S-adenosylhomocysteine hydrolase]] |
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID:022349223</ref>< | + | <ref group="xtra">PMID:022349223</ref><references group="xtra"/><references/> |
[[Category: Adenosylhomocysteinase]] | [[Category: Adenosylhomocysteinase]] | ||
| - | [[Category: | + | [[Category: European yellow lupin]] |
[[Category: Brzezinski, K.]] | [[Category: Brzezinski, K.]] | ||
[[Category: Jaskolski, M.]] | [[Category: Jaskolski, M.]] | ||
Revision as of 15:24, 19 February 2014
Contents |
Crystal structure of Lupinus luteus S-adenosyl-L-homocysteine hydrolase in complex with cordycepin
Template:ABSTRACT PUBMED 22349223
Function
[SAHH_LUPLU] Adenosylhomocysteine is a competitive inhibitor of S-adenosyl-L-methionine-dependent methyl transferase reactions; therefore adenosylhomocysteinase may play a key role in the control of methylations via regulation of the intracellular concentration of adenosylhomocysteine (By similarity).
About this Structure
3onf is a 2 chain structure with sequence from European yellow lupin. Full crystallographic information is available from OCA.
See Also
Reference
- Brzezinski K, Dauter Z, Jaskolski M. High-resolution structures of complexes of plant S-adenosyl-L-homocysteine hydrolase (Lupinus luteus). Acta Crystallogr D Biol Crystallogr. 2012 Mar;68(Pt 3):218-31. Epub 2012 Feb 7. PMID:22349223 doi:10.1107/S0907444911055090
