3gbp
From Proteopedia
(New page: 200px<br /><applet load="3gbp" size="450" color="white" frame="true" align="right" spinBox="true" caption="3gbp, resolution 2.4Å" /> '''STRUCTURE OF THE PERI...) |
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| - | [[Image:3gbp.gif|left|200px]]<br /><applet load="3gbp" size=" | + | [[Image:3gbp.gif|left|200px]]<br /><applet load="3gbp" size="350" color="white" frame="true" align="right" spinBox="true" |
caption="3gbp, resolution 2.4Å" /> | caption="3gbp, resolution 2.4Å" /> | ||
'''STRUCTURE OF THE PERIPLASMIC GLUCOSE/GALACTOSE RECEPTOR OF SALMONELLA TYPHIMURIUM'''<br /> | '''STRUCTURE OF THE PERIPLASMIC GLUCOSE/GALACTOSE RECEPTOR OF SALMONELLA TYPHIMURIUM'''<br /> | ||
==Overview== | ==Overview== | ||
| - | The X-ray structure of the periplasmic glucose/galactose receptor (binding | + | The X-ray structure of the periplasmic glucose/galactose receptor (binding protein) of Salmonella typhimurium has been solved by the method of multiple isomorphous replacement and refined to a resolution of 2.4 A with an R-factor of 15.8%. The protein consists of two highly-similar structural domains with a bound sugar molecule trapped between. A combined sequence/structural approach is used to compare the structure of this protein to a similar arabinose receptor. The new sequence alignment obtained is used to analyze a number of features conserved for structural and functional reasons. This information allowed the prediction of similar features within the sequence of the analogous ribose receptor. Some of the consequences of the structures for chemotaxis and transport are discussed. |
==About this Structure== | ==About this Structure== | ||
| - | 3GBP is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Salmonella_typhimurium Salmonella typhimurium] with GLC and CA as [http://en.wikipedia.org/wiki/ligands ligands]. This structure | + | 3GBP is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Salmonella_typhimurium Salmonella typhimurium] with <scene name='pdbligand=GLC:'>GLC</scene> and <scene name='pdbligand=CA:'>CA</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. This structure supersedes the now removed PDB entry 1GBP. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GBP OCA]. |
==Reference== | ==Reference== | ||
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[[Category: Salmonella typhimurium]] | [[Category: Salmonella typhimurium]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
| - | [[Category: Mowbray, S | + | [[Category: Mowbray, S L.]] |
[[Category: CA]] | [[Category: CA]] | ||
[[Category: GLC]] | [[Category: GLC]] | ||
[[Category: periplasmic binding protein]] | [[Category: periplasmic binding protein]] | ||
| - | ''Page seeded by [http:// | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 19:09:27 2008'' |
Revision as of 17:09, 21 February 2008
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STRUCTURE OF THE PERIPLASMIC GLUCOSE/GALACTOSE RECEPTOR OF SALMONELLA TYPHIMURIUM
Overview
The X-ray structure of the periplasmic glucose/galactose receptor (binding protein) of Salmonella typhimurium has been solved by the method of multiple isomorphous replacement and refined to a resolution of 2.4 A with an R-factor of 15.8%. The protein consists of two highly-similar structural domains with a bound sugar molecule trapped between. A combined sequence/structural approach is used to compare the structure of this protein to a similar arabinose receptor. The new sequence alignment obtained is used to analyze a number of features conserved for structural and functional reasons. This information allowed the prediction of similar features within the sequence of the analogous ribose receptor. Some of the consequences of the structures for chemotaxis and transport are discussed.
About this Structure
3GBP is a Single protein structure of sequence from Salmonella typhimurium with and as ligands. This structure supersedes the now removed PDB entry 1GBP. Full crystallographic information is available from OCA.
Reference
Structure of the periplasmic glucose/galactose receptor of Salmonella typhimurium., Mowbray SL, Smith RD, Cole LB, Receptor. 1990-1991 Winter;1(1-2):41-53. PMID:1967096
Page seeded by OCA on Thu Feb 21 19:09:27 2008
