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4cko

From Proteopedia

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Current revision (17:10, 19 February 2014) (edit) (undo)
(Redirecting to 4cq1)
 
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{{STRUCTURE_4cko| PDB=4cko | SCENE= }}
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#REDIRECT [[4cq1]] This PDB entry is obsolete and replaced by 4cq1
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===Crystal structure of the neuronal isoform of PTB===
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==Function==
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[[http://www.uniprot.org/uniprot/PTBP2_HUMAN PTBP2_HUMAN]] RNA-binding protein which binds to intronic polypyrimidine tracts and mediates negative regulation of exons splicing. May antagonize in a tissue-specific manner the ability of NOVA1 to activate exon selection. Beside its function in pre-mRNA splicing, plays also a role in the regulation of translation. Isoform 5 has a reduced affinity for RNA.<ref>PMID:11003644</ref> <ref>PMID:12667457</ref>
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==About this Structure==
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[[4cko]] is a 8 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CKO OCA].
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==Reference==
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<references group="xtra"/><references/>
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[[Category: Buckroyd, A N.]]
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[[Category: Curry, S.]]
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[[Category: Joshi, A.]]
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[[Category: Brptb]]
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[[Category: Rna binding protein]]
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[[Category: Translation]]
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Current revision

  1. REDIRECT 4cq1 This PDB entry is obsolete and replaced by 4cq1

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