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4c0h
From Proteopedia
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| - | + | {{STRUCTURE_4c0h| PDB=4c0h | SCENE= }} | |
| + | ===Extended interface between Pcf11p and Clp1p and structural basis for ATP loss in Gly135Arg point mutant=== | ||
| + | {{ABSTRACT_PUBMED_24508575}} | ||
| - | + | ==Function== | |
| + | [[http://www.uniprot.org/uniprot/CLP1_YEAST CLP1_YEAST]] Component of the cleavage factor IA (CFIA) complex, which is involved in the endonucleolytic cleavage during polyadenylation-dependent pre-mRNA 3'-end formation and cooperates with the cleavage factor NAB4/CFIB and the cleavage and polyadenylation factor (CPF) complex.<ref>PMID:11344258</ref> | ||
| - | + | ==About this Structure== | |
| + | [[4c0h]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4C0H OCA]. | ||
| - | + | ==Reference== | |
| + | <ref group="xtra">PMID:024508575</ref><references group="xtra"/><references/> | ||
| + | [[Category: Dupin, A F.]] | ||
| + | [[Category: Fribourg, S.]] | ||
| + | [[Category: 3' end mrna processing]] | ||
| + | [[Category: Mutant]] | ||
| + | [[Category: Transcription]] | ||
Revision as of 17:17, 19 February 2014
Contents |
Extended interface between Pcf11p and Clp1p and structural basis for ATP loss in Gly135Arg point mutant
Template:ABSTRACT PUBMED 24508575
Function
[CLP1_YEAST] Component of the cleavage factor IA (CFIA) complex, which is involved in the endonucleolytic cleavage during polyadenylation-dependent pre-mRNA 3'-end formation and cooperates with the cleavage factor NAB4/CFIB and the cleavage and polyadenylation factor (CPF) complex.[1]
About this Structure
4c0h is a 4 chain structure. Full crystallographic information is available from OCA.
Reference
- Dupin AF, Fribourg S. Structural basis for ATP loss by Clp1p in a G135R mutant protein. Biochimie. 2014 Feb 5. pii: S0300-9084(14)00035-2. doi:, 10.1016/j.biochi.2014.01.017. PMID:24508575 doi:http://dx.doi.org/10.1016/j.biochi.2014.01.017
- ↑ Gross S, Moore C. Five subunits are required for reconstitution of the cleavage and polyadenylation activities of Saccharomyces cerevisiae cleavage factor I. Proc Natl Acad Sci U S A. 2001 May 22;98(11):6080-5. Epub 2001 May 8. PMID:11344258 doi:http://dx.doi.org/10.1073/pnas.101046598
