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4ofd

From Proteopedia

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m (Protected "4ofd" [edit=sysop:move=sysop])
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'''Unreleased structure'''
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{{STRUCTURE_4ofd| PDB=4ofd | SCENE= }}
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===Crystal Structure of mouse Neph1 D1-D2===
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{{ABSTRACT_PUBMED_24485456}}
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The entry 4ofd is ON HOLD
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==Function==
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[[http://www.uniprot.org/uniprot/KIRR1_MOUSE KIRR1_MOUSE]] Plays a significant role in the normal development and function of the glomerular permeability. Is a signaling protein that needs the presence of TEC kinases to fully trans-activate the transcription factor AP-1.<ref>PMID:11416156</ref>
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Authors: Ozkan, E., Garcia, K.C.
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==About this Structure==
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[[4ofd]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4OFD OCA].
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Description: Crystal Structure of mouse Neph1 D1-D2
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==Reference==
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<ref group="xtra">PMID:024485456</ref><references group="xtra"/><references/>
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[[Category: Garcia, K C.]]
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[[Category: Ozkan, E.]]
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[[Category: Blood filtration]]
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[[Category: Cell adhesion]]
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[[Category: Extracellular]]
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[[Category: Immunoglobulin superfamily]]
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[[Category: Kidney]]
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[[Category: Membrane]]
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[[Category: N-linked glycosylation]]
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[[Category: Protein binding]]
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[[Category: Signaling protein]]

Revision as of 17:29, 19 February 2014

Template:STRUCTURE 4ofd

Contents

Crystal Structure of mouse Neph1 D1-D2

Template:ABSTRACT PUBMED 24485456

Function

[KIRR1_MOUSE] Plays a significant role in the normal development and function of the glomerular permeability. Is a signaling protein that needs the presence of TEC kinases to fully trans-activate the transcription factor AP-1.[1]

About this Structure

4ofd is a 2 chain structure. Full crystallographic information is available from OCA.

Reference

  • Ozkan E, Chia PH, Wang RR, Goriatcheva N, Borek D, Otwinowski Z, Walz T, Shen K, Garcia KC. Extracellular Architecture of the SYG-1/SYG-2 Adhesion Complex Instructs Synaptogenesis. Cell. 2014 Jan 30;156(3):482-94. doi: 10.1016/j.cell.2014.01.004. PMID:24485456 doi:http://dx.doi.org/10.1016/j.cell.2014.01.004
  1. ↑ Donoviel DB, Freed DD, Vogel H, Potter DG, Hawkins E, Barrish JP, Mathur BN, Turner CA, Geske R, Montgomery CA, Starbuck M, Brandt M, Gupta A, Ramirez-Solis R, Zambrowicz BP, Powell DR. Proteinuria and perinatal lethality in mice lacking NEPH1, a novel protein with homology to NEPHRIN. Mol Cell Biol. 2001 Jul;21(14):4829-36. PMID:11416156 doi:http://dx.doi.org/10.1128/MCB.21.14.4829-4836.2001

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