4bwl

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'''Unreleased structure'''
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{{STRUCTURE_4bwl| PDB=4bwl | SCENE= }}
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===Structure of the Y137A mutant of E. coli N-acetylneuraminic acid lyase in complex with pyruvate, N-acetyl-D-mannosamine and N- acetylneuraminic acid===
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The entry 4bwl is ON HOLD until Paper Publication
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==Function==
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[[http://www.uniprot.org/uniprot/NANA_ECOLI NANA_ECOLI]] Catalyzes the cleavage of N-acetylneuraminic acid (sialic acid) to form pyruvate and N-acetylmannosamine via a Schiff base intermediate.[HAMAP-Rule:MF_01237]
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Authors: Campeotto, I., Phillips, S.E.V., Pearson, A.R., Nelson, A., Berry, A.
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==About this Structure==
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[[4bwl]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BWL OCA].
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Description: Structure of the Y137A mutant of E. coli N-acetylneuraminic acid lyase in complex with pyruvate, N-acetyl-D-mannosamine and N-acetylneuraminic acid
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[[Category: N-acetylneuraminate lyase]]
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[[Category: Berry, A.]]
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[[Category: Campeotto, I.]]
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[[Category: Nelson, A.]]
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[[Category: Pearson, A R.]]
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[[Category: Phillips, S E.V.]]
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[[Category: Directed evolution]]
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[[Category: Lyase]]
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[[Category: Protein engineering]]
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[[Category: Substrate specificity]]

Revision as of 17:43, 19 February 2014

Template:STRUCTURE 4bwl

Structure of the Y137A mutant of E. coli N-acetylneuraminic acid lyase in complex with pyruvate, N-acetyl-D-mannosamine and N- acetylneuraminic acid

Function

[NANA_ECOLI] Catalyzes the cleavage of N-acetylneuraminic acid (sialic acid) to form pyruvate and N-acetylmannosamine via a Schiff base intermediate.[HAMAP-Rule:MF_01237]

About this Structure

4bwl is a 4 chain structure. Full crystallographic information is available from OCA.

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