Metabotropic glutamate receptor
From Proteopedia
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| - | [[Metabotropic glutamate receptor|Metabotropic glutamate receptors]] are [[Glutamate Receptors|glutamate receptors]] that | + | [[Metabotropic glutamate receptor|Metabotropic glutamate receptors]] are [[Glutamate Receptors|glutamate receptors]] that activate ion channels indirectly through a signalling cascade involving G proteins. They are members of the large class of seven-transmembrane domain receptors, the [[G protein-coupled receptor|G protein-coupled receptors]]. |
<Structure load='1isr' size='500' side='right' caption='Structure of the binding domain of the Metabotropic Glutamate Receptor, GluR1, bound to glutamateand gadolinium ions ([[1isr]])' scene=' '/> | <Structure load='1isr' size='500' side='right' caption='Structure of the binding domain of the Metabotropic Glutamate Receptor, GluR1, bound to glutamateand gadolinium ions ([[1isr]])' scene=' '/> | ||
Revision as of 07:31, 2 March 2014
Metabotropic glutamate receptors are glutamate receptors that activate ion channels indirectly through a signalling cascade involving G proteins. They are members of the large class of seven-transmembrane domain receptors, the G protein-coupled receptors.
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Articles in Proteopedia concerning Toll-like Receptors include:
3D structures of metabotropic glutamate receptor
Metabotropic glutamate receptor 1
1ewt, 1ewv - rMGluR1 ligand-binding domain
3ks9 – hMGluR1 (mutant) + antagonist
1isr, 1ewk – rMGluR1 ligand-binding domain + Glu
1iss - rMGluR1 ligand-binding domain + antagonist
Metabotropic glutamate receptor 3
2e4u – hMGluR3 ligand-binding domain (mutant) + Glu
2e4v, 2e4w, 2e4x, 2e4y, 2e4z - hMGluR3 ligand-binding domain (mutant) + agonist
Metabotropic glutamate receptor 5
3lmk – hMGluR5 ligand-binding domain (mutant) + positive allosteric modulator + Glu
Metabotropic glutamate receptor 7
3mq4 – hMGluR7 ligand-binding domain + antagonist
See Also
[Membrane Channels & Pumps]]
Ionotropic_Glutamate_Receptors
Alzheimer's Disease
Proteopedia Page Contributors and Editors (what is this?)
Michal Harel, Alexander Berchansky, Wayne Decatur, Nikki Hunter
