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4nb2

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'''Unreleased structure'''
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{{STRUCTURE_4nb2| PDB=4nb2 | SCENE= }}
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===Crystal Structure of FosB from Staphylococcus aureus at 1.89 Angstrom Resolution - Apo structure===
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{{ABSTRACT_PUBMED_24447055}}
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The entry 4nb2 is ON HOLD until Paper Publication
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==Function==
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[[http://www.uniprot.org/uniprot/FOSB_STAAN FOSB_STAAN]] Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor (By similarity).
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Authors: Goodman, M.C., Jagessar, K., Harp, J., Keithly, M.E.
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==About this Structure==
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[[4nb2]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NB2 OCA].
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Description: Crystal Structure of FosB from Staphylococcus aureus at 1.89 Angstrom Resolution -Apo structure
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==Reference==
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<ref group="xtra">PMID:024447055</ref><references group="xtra"/><references/>
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[[Category: Goodman, M C.]]
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[[Category: Harp, J.]]
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[[Category: Jagessar, K.]]
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[[Category: Keithly, M E.]]
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[[Category: Bacillithiol-s-transferase]]
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[[Category: Transferase]]

Revision as of 17:58, 3 March 2014

Template:STRUCTURE 4nb2

Contents

Crystal Structure of FosB from Staphylococcus aureus at 1.89 Angstrom Resolution - Apo structure

Template:ABSTRACT PUBMED 24447055

Function

[FOSB_STAAN] Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor (By similarity).

About this Structure

4nb2 is a 2 chain structure. Full crystallographic information is available from OCA.

Reference

  • Thompson MK, Keithly ME, Goodman MC, Hammer ND, Cook PD, Jagessar KL, Harp J, Skaar EP, Armstrong RN. Structure and Function of the Genomically Encoded Fosfomycin Resistance Enzyme, FosB, from Staphylococcus aureus. Biochemistry. 2014 Feb 4;53(4):755-65. doi: 10.1021/bi4015852. Epub 2014 Jan 21. PMID:24447055 doi:http://dx.doi.org/10.1021/bi4015852

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OCA

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