4lzj

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
'''Unreleased structure'''
+
{{STRUCTURE_4lzj| PDB=4lzj | SCENE= }}
 +
===Crystal Structure of MurQ from H.influenzae with bound inhibitor===
 +
{{ABSTRACT_PUBMED_24251551}}
-
The entry 4lzj is ON HOLD until sometime in the future
+
==Function==
 +
[[http://www.uniprot.org/uniprot/MURQ_HAEIN MURQ_HAEIN]] Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate. Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity).
-
Authors: Hazra, S., Blanchard, J.
+
==About this Structure==
 +
[[4lzj]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LZJ OCA].
-
Description: Crystal Structure of MurQ from H.influenzae with bound inhibitor
+
==Reference==
 +
<ref group="xtra">PMID:024251551</ref><references group="xtra"/><references/>
 +
[[Category: N-acetylmuramic acid 6-phosphate etherase]]
 +
[[Category: Blanchard, J.]]
 +
[[Category: Hazra, S.]]
 +
[[Category: Alpha-beta-alpha sandwich]]
 +
[[Category: D-muramitol 6-phosphate]]
 +
[[Category: Lyase-lyase inhibitor complex]]
 +
[[Category: Murq]]
 +
[[Category: Protein-ligand complex]]
 +
[[Category: Yfeu]]

Revision as of 17:58, 3 March 2014

Template:STRUCTURE 4lzj

Contents

Crystal Structure of MurQ from H.influenzae with bound inhibitor

Template:ABSTRACT PUBMED 24251551

Function

[MURQ_HAEIN] Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate. Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity).

About this Structure

4lzj is a 4 chain structure. Full crystallographic information is available from OCA.

Reference

  • Hadi T, Hazra S, Tanner ME, Blanchard JS. Structure of MurNAc 6-phosphate hydrolase (MurQ) from Haemophilus influenzae with a bound inhibitor. Biochemistry. 2013 Dec 23;52(51):9358-66. doi: 10.1021/bi4010446. Epub 2013 Nov, 22. PMID:24251551 doi:http://dx.doi.org/10.1021/bi4010446

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/4lzj"
Personal tools