3wqm

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m (Protected "3wqm" [edit=sysop:move=sysop])
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'''Unreleased structure'''
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{{STRUCTURE_3wqm| PDB=3wqm | SCENE= }}
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===Crystal structure of Rv3378c with inhibitor BPH-629===
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{{ABSTRACT_PUBMED_24475925}}
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The entry 3wqm is ON HOLD
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==Function==
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[[http://www.uniprot.org/uniprot/TUBOL_MYCTU TUBOL_MYCTU]] Catalyzes the PP-removal from tuberculosinyl diphosphate to produce both tubercilosinol and isotuberculosinol. Can also use labdadienyl diphosphates, copalyl diphosphate (CDP), ent-CDP and syn-CDP in vitro.
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Authors: Chan, H.C., Feng,X., Ko,T.P., Huang, C.H., Hu,Y., Zheng,Y., Bogue, S., Nakano, C., Hoshino, T., Zhang, L., Lv, P., Liu, W., Crick, D., Liang, P. H., Wang, H. J., Oldfield, E, Guo, R. T.
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==About this Structure==
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[[3wqm]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WQM OCA].
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Description: Crystal structure of Rv3378c with inhibitor BPH-629
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==Reference==
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<ref group="xtra">PMID:024475925</ref><references group="xtra"/><references/>
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[[Category: Bogue, S.]]
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[[Category: Chan, H C.]]
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[[Category: Crick, D C.]]
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[[Category: Feng, X.]]
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[[Category: Guo, R T.]]
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[[Category: Hoshino, T.]]
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[[Category: Hu, Y.]]
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[[Category: Huang, C H.]]
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[[Category: Ko, T P.]]
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[[Category: Liang, P H.]]
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[[Category: Liu, W.]]
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[[Category: Lv, P.]]
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[[Category: Nakano, C.]]
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[[Category: Oldfield, E.]]
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[[Category: Wang, A H.]]
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[[Category: Zhang, L.]]
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[[Category: Zheng, Y.]]
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[[Category: Diterpene synthase]]
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[[Category: Hydrolase-hydrolase inhibitor complex]]

Revision as of 18:14, 3 March 2014

Template:STRUCTURE 3wqm

Contents

Crystal structure of Rv3378c with inhibitor BPH-629

Template:ABSTRACT PUBMED 24475925

Function

[TUBOL_MYCTU] Catalyzes the PP-removal from tuberculosinyl diphosphate to produce both tubercilosinol and isotuberculosinol. Can also use labdadienyl diphosphates, copalyl diphosphate (CDP), ent-CDP and syn-CDP in vitro.

About this Structure

3wqm is a 1 chain structure. Full crystallographic information is available from OCA.

Reference

  • Chan HC, Feng X, Ko TP, Huang CH, Hu Y, Zheng Y, Bogue S, Nakano C, Hoshino T, Zhang L, Lv P, Liu W, Crick DC, Liang PH, Wang AH, Oldfield E, Guo RT. Structure and Inhibition of Tuberculosinol Synthase and Decaprenyl Diphosphate Synthase from Mycobacterium tuberculosis. J Am Chem Soc. 2014 Feb 5. PMID:24475925 doi:http://dx.doi.org/10.1021/ja413127v

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OCA

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