4irb

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'''Unreleased structure'''
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{{STRUCTURE_4irb| PDB=4irb | SCENE= }}
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===Crystal Structure of Vaccinia Virus Uracil DNA Glycosylase Mutant del171-172D4===
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{{ABSTRACT_PUBMED_23519808}}
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The entry 4irb is ON HOLD until Paper Publication
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==Function==
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[[http://www.uniprot.org/uniprot/UNG_VACCA UNG_VACCA]] Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. Also part of a heterodimeric processivity factor which potentiates the DNA polymerase activity. Binds to DNA.
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Authors: Schormann, N., Zhukovskaya, N., Sartmatova, D., Nuth, M., Ricciardi, R.P., Chattopadhyay, D.
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==About this Structure==
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[[4irb]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4IRB OCA].
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Description: Crystal Structure of Vaccinia Virus Uracil DNA Glycosylase Mutant del171-172D4
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==Reference==
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<ref group="xtra">PMID:023519808</ref><references group="xtra"/><references/>
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[[Category: Uracil-DNA glycosylase]]
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[[Category: Chattopadhyay, D.]]
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[[Category: Nuth, M.]]
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[[Category: Ricciardi, R P.]]
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[[Category: Sartmatova, D.]]
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[[Category: Schormann, N.]]
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[[Category: Zhukovskaya, N.]]
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[[Category: Beta- sheets at n- and c-terminus]]
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[[Category: Binding partners a20 and dna]]
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[[Category: Component of processivity factor]]
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[[Category: Dimeric assembly]]
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[[Category: Dna repair hydrolase]]
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[[Category: Hydrolase]]
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[[Category: Parallel beta-sheet of 4 strands in the order 2134]]
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[[Category: Viral protein]]

Revision as of 18:15, 3 March 2014

Template:STRUCTURE 4irb

Contents

Crystal Structure of Vaccinia Virus Uracil DNA Glycosylase Mutant del171-172D4

Template:ABSTRACT PUBMED 23519808

Function

[UNG_VACCA] Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. Also part of a heterodimeric processivity factor which potentiates the DNA polymerase activity. Binds to DNA.

About this Structure

4irb is a 4 chain structure. Full crystallographic information is available from OCA.

Reference

  • Sartmatova D, Nash T, Schormann N, Nuth M, Ricciardi R, Banerjee S, Chattopadhyay D. Crystallization and preliminary X-ray diffraction analysis of three recombinant mutants of Vaccinia virus uracil DNA glycosylase. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2013 Mar 1;69(Pt 3):295-301., doi: 10.1107/S1744309113002716. Epub 2013 Feb 23. PMID:23519808 doi:http://dx.doi.org/10.1107/S1744309113002716

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OCA

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