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4nn2

From Proteopedia

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'''Unreleased structure'''
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{{STRUCTURE_4nn2| PDB=4nn2 | SCENE= }}
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===Protein Crystal Structure of Human Borjeson-Forssman-Lehmann Syndrome Associated Protein PHF6===
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The entry 4nn2 is ON HOLD until Nov 16 2015
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==Disease==
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[[http://www.uniprot.org/uniprot/PHF6_HUMAN PHF6_HUMAN]] Borjeson-Forssman-Lehmann syndrome. The disease is caused by mutations affecting the gene represented in this entry.
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Authors: Liu, Z., Li,F., Zhang, J., Mei,Y., Wu, J., Shi,Y.
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==Function==
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[[http://www.uniprot.org/uniprot/PHF6_HUMAN PHF6_HUMAN]] Transcriptional regulator that associates with ribosomal RNA promoters and suppresses ribosomal RNA (rRNA) transcription.<ref>PMID:23229552</ref>
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Description: Protein Crystal Structure
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==About this Structure==
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[[4nn2]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NN2 OCA].
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==Reference==
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<references group="xtra"/><references/>
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[[Category: Li,F.]]
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[[Category: Liu, Z.]]
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[[Category: Mei,Y.]]
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[[Category: Shi,Y.]]
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[[Category: Wu, J.]]
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[[Category: Zhang, J.]]
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[[Category: Transcription]]
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[[Category: Zinc finger]]

Revision as of 18:26, 3 March 2014

Template:STRUCTURE 4nn2

Contents

Protein Crystal Structure of Human Borjeson-Forssman-Lehmann Syndrome Associated Protein PHF6

Disease

[PHF6_HUMAN] Borjeson-Forssman-Lehmann syndrome. The disease is caused by mutations affecting the gene represented in this entry.

Function

[PHF6_HUMAN] Transcriptional regulator that associates with ribosomal RNA promoters and suppresses ribosomal RNA (rRNA) transcription.[1]

About this Structure

4nn2 is a 2 chain structure. Full crystallographic information is available from OCA.

Reference

  1. ↑ Wang J, Leung JW, Gong Z, Feng L, Shi X, Chen J. PHF6 regulates cell cycle progression by suppressing ribosomal RNA synthesis. J Biol Chem. 2013 Feb 1;288(5):3174-83. doi: 10.1074/jbc.M112.414839. Epub 2012, Dec 10. PMID:23229552 doi:http://dx.doi.org/10.1074/jbc.M112.414839

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OCA

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