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Forkhead box protein

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===FOXO3===
===FOXO3===
-
[[2uzk]] – hFOXO3 DNA-binding domain + DNA
+
[[2uzk]] – hFOXO3 DNA-binding domain + DNA<br />
 +
[[2k86]] - hFOXO3 DNA-binding domain – NMR<br />
 +
[[2lqh]], [[2lqi]] - hFOXO3 transactivation domain + CREB-binding protein – NMR<br />
===FOXO4===
===FOXO4===
Line 35: Line 37:
===[[FOXP3]]===
===[[FOXP3]]===
-
[[3qrf]] – hFOXP3 DNA-binding domain + nuclear factor of activated T-cell + DNA
+
[[3qrf]] – hFOXP3 DNA-binding domain + nuclear factor of activated T-cell + DNA<br />
 +
[[4i1l]] – mFOXP3 residues 189-276 – mouse<br />
===FOXK2===
===FOXK2===
Line 43: Line 46:
===FOXK1===
===FOXK1===
-
[[2a3s]], [[2d2w]] – FOXK1 DNA-binding domain – mouse – NMR
+
[[2a3s]], [[2d2w]] – mFOXK1 DNA-binding domain – NMR
===FOXM1===
===FOXM1===

Revision as of 11:35, 9 March 2014

Template:STRUCTURE 3co6 Forkhead box proteins (FOX) are transcription factors involved in regulation of gene expression. They contain a DNA-binding motif of 80-100 amino acids having a winged-helix shape. For details on individual FOX proteins, see

See also Transcription and RNA Processing and Neurodevelopmental Disorders.

Contents

3D structures of FOX

Updated on 09-March-2014

FOXO1

3co6, 3coa – hFOXO1 + DNA – human

FOXO3

2uzk – hFOXO3 DNA-binding domain + DNA
2k86 - hFOXO3 DNA-binding domain – NMR
2lqh, 2lqi - hFOXO3 transactivation domain + CREB-binding protein – NMR

FOXO4

3l2c – hFOXO4 DNA-binding domain + DNA

FOXP1

2kiu – hFOXP1 DNA-binding domain (mutant) - NMR

FOXP2

2a07 – hFOXP2 + DNA
2as5 – hFOXP2 DNA-binding domain + nuclear factor of activated T-cell + DNA

FOXP3

3qrf – hFOXP3 DNA-binding domain + nuclear factor of activated T-cell + DNA
4i1l – mFOXP3 residues 189-276 – mouse

FOXK2

2c6y – hFOXK2 DNA-binding domain + DNA

FOXK1

2a3s, 2d2w – mFOXK1 DNA-binding domain – NMR

FOXM1

3g73 – hFOXM1 DNA-binding domain + DNA

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky, David Canner

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