Glutaminase
From Proteopedia
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[[3if5]], [[3ih8]], [[3ih9]], [[3agd]] – MlGLN – ''Micrococcus luteus''<br /> | [[3if5]], [[3ih8]], [[3ih9]], [[3agd]] – MlGLN – ''Micrococcus luteus''<br /> | ||
| + | [[2pby]] – GLN – ''Geobacillus kaustophilus''<br /> | ||
| + | [[2zk9]] – CpGLN – ''Chryseobacterium proteolyticum''<br /> | ||
| + | [[3a54]], [[3a55]], [[3a56]] – CpGLN (mutant)<br /> | ||
[[3agf]] - BsGLN – ''Bacillus subtilis''<br /> | [[3agf]] - BsGLN – ''Bacillus subtilis''<br /> | ||
[[3ss3]], [[3ss4]] – mGLN C – mouse<br /> | [[3ss3]], [[3ss4]] – mGLN C – mouse<br /> | ||
| - | [[3voy]] – hGLN – human | + | [[4jkt]] - mGLN kidney isoform<br /> |
| + | [[3voy]] – hGLN kidney isoform – human<br /> | ||
| + | [[4bqm]] - hGLN liver isoform<br /> | ||
===GLN complex=== | ===GLN complex=== | ||
Revision as of 13:00, 11 March 2014
Glutaminase (GLN) catalyzes the conversion of glutamine (Gln) to glutamic acid (Glu). GLN is present at the axonal termini of neurons where GA functions as a neurotransmitter. ADP is an activator of GLN. GLN is a homodimer. In human GLN is found as 2 isozymes – GLN and GLN 2. Glutaminase-asparaginase (GLN-ASN) can amidohydrolase both glutamine and asparagine to their corresponding Glu and Asp.
Contents |
3D structures of glutaminase
Updated on 11-March-2014
GLN
3if5, 3ih8, 3ih9, 3agd – MlGLN – Micrococcus luteus
2pby – GLN – Geobacillus kaustophilus
2zk9 – CpGLN – Chryseobacterium proteolyticum
3a54, 3a55, 3a56 – CpGLN (mutant)
3agf - BsGLN – Bacillus subtilis
3ss3, 3ss4 – mGLN C – mouse
4jkt - mGLN kidney isoform
3voy – hGLN kidney isoform – human
4bqm - hGLN liver isoform
GLN complex
3brm – BsGLN + norleucine
3czd, 3unw – hGLN + Glu
3vp0 – hGLN + Gln
3uo9, 3voz, 3vp2, 3vp3, 3vp4 - hGLN + inhibitor
3iha, 3ihb, 3age - MlGLN + Glu
3ss5 – mGLN + Glu
3vp1 - hGLN + inhibitor + Glu
GLN-ASN
1agx – GLN-ASN – Acinetobacter glutaminacificans
3pga, 4pga – PsGLN-ASN – Pseudomonas
1djo, 1djp - PsGLN-ASN + norvaline derivative
1u60 - YbaS
3brm - YbgJ in a complex with DON
1mki - YbgJ free
Created with the participation of Lindsey Butler.
