452d

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(New page: 200px<br /><applet load="452d" size="350" color="white" frame="true" align="right" spinBox="true" caption="452d, resolution 1.6&Aring;" /> '''ACRIDINE BINDING TO D...)
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Major groove binding and 'DNA-induced' fit in the intercalation of a derivative of the mixed topoisomerase I/II poison N-(2-(dimethylamino)ethyl)acridine-4-carboxamide (DACA) into DNA: X-ray structure complexed to d(CG(5-BrU)ACG)2 at 1.3-A resolution., Todd AK, Adams A, Thorpe JH, Denny WA, Wakelin LP, Cardin CJ, J Med Chem. 1999 Feb 25;42(4):536-40. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=10052960 10052960]
Major groove binding and 'DNA-induced' fit in the intercalation of a derivative of the mixed topoisomerase I/II poison N-(2-(dimethylamino)ethyl)acridine-4-carboxamide (DACA) into DNA: X-ray structure complexed to d(CG(5-BrU)ACG)2 at 1.3-A resolution., Todd AK, Adams A, Thorpe JH, Denny WA, Wakelin LP, Cardin CJ, J Med Chem. 1999 Feb 25;42(4):536-40. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=10052960 10052960]
[[Category: Protein complex]]
[[Category: Protein complex]]
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[[Category: Cardin, C.J.]]
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[[Category: Cardin, C J.]]
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[[Category: Thorpe, J.H.]]
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[[Category: Thorpe, J H.]]
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[[Category: Todd, A.K.]]
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[[Category: Todd, A K.]]
[[Category: 9AD]]
[[Category: 9AD]]
[[Category: MPD]]
[[Category: MPD]]
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[[Category: intercalation]]
[[Category: intercalation]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jan 29 21:44:03 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 19:12:30 2008''

Revision as of 17:12, 21 February 2008

Image:452d.gif

452d, resolution 1.6Å

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ACRIDINE BINDING TO DNA

About this Structure

452D is a Protein complex structure of sequences from [1] with and as ligands. Full crystallographic information is available from OCA.

Reference

Major groove binding and 'DNA-induced' fit in the intercalation of a derivative of the mixed topoisomerase I/II poison N-(2-(dimethylamino)ethyl)acridine-4-carboxamide (DACA) into DNA: X-ray structure complexed to d(CG(5-BrU)ACG)2 at 1.3-A resolution., Todd AK, Adams A, Thorpe JH, Denny WA, Wakelin LP, Cardin CJ, J Med Chem. 1999 Feb 25;42(4):536-40. PMID:10052960

Page seeded by OCA on Thu Feb 21 19:12:30 2008

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