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3wj9

From Proteopedia

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'''Unreleased structure'''
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{{STRUCTURE_3wj9| PDB=3wj9 | SCENE= }}
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===Crystal structure of the eukaryotic initiation factor===
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{{ABSTRACT_PUBMED_24569939}}
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The entry 3wj9 is ON HOLD
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==Function==
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[[http://www.uniprot.org/uniprot/EIF2A_SCHPO EIF2A_SCHPO]] Functions in the early steps of protein synthesis of a small number of specific mRNAs. Acts by directing the binding of methionyl-tRNAi to 40S ribosomal subunits. In contrast to the eIF-2 complex, it binds methionyl-tRNAi to 40 S subunits in a codon-dependent manner, whereas the eIF-2 complex binds methionyl-tRNAi to 40 S subunits in a GTP-dependent manner. May act by impiging the expression of specific proteins (By similarity).
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Authors: Kashiwagi, K., Ito, T., Yokoyama, S.
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==About this Structure==
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[[3wj9]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WJ9 OCA].
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Description: Crystal structure of the eukaryotic initiation factor
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==Reference==
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<ref group="xtra">PMID:024569939</ref><references group="xtra"/><references/>
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[[Category: Ito, T.]]
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[[Category: Kashiwagi, K.]]
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[[Category: Yokoyama, S.]]
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[[Category: Beta-propeller]]
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[[Category: Translation]]

Revision as of 13:35, 12 March 2014

Template:STRUCTURE 3wj9

Contents

Crystal structure of the eukaryotic initiation factor

Template:ABSTRACT PUBMED 24569939

Function

[EIF2A_SCHPO] Functions in the early steps of protein synthesis of a small number of specific mRNAs. Acts by directing the binding of methionyl-tRNAi to 40S ribosomal subunits. In contrast to the eIF-2 complex, it binds methionyl-tRNAi to 40 S subunits in a codon-dependent manner, whereas the eIF-2 complex binds methionyl-tRNAi to 40 S subunits in a GTP-dependent manner. May act by impiging the expression of specific proteins (By similarity).

About this Structure

3wj9 is a 2 chain structure. Full crystallographic information is available from OCA.

Reference

Proteopedia Page Contributors and Editors (what is this?)

OCA

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