2kzk

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[[Image:2kzk.png|left|200px]]
 
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{{STRUCTURE_2kzk| PDB=2kzk | SCENE= }}
{{STRUCTURE_2kzk| PDB=2kzk | SCENE= }}
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===Solution structure of alpha-mannosidase binding domain of Atg34===
===Solution structure of alpha-mannosidase binding domain of Atg34===
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{{ABSTRACT_PUBMED_20659891}}
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{{ABSTRACT_PUBMED_020659891}}
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==Function==
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[[http://www.uniprot.org/uniprot/ATG34_YEAST ATG34_YEAST]] Cargo-receptor protein involved in the cytoplasm to vacuole transport (Cvt) and in autophagy. Recognizes cargo proteins, such as AMS1 and delivers them to the pre-autophagosomal structure for eventual engulfment by the autophagosome and targeting to the vacuole.<ref>PMID:20639194</ref> <ref>PMID:20659891</ref>
==About this Structure==
==About this Structure==
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[[2kzk]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KZK OCA].
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[[2kzk]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_18824 Atcc 18824]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KZK OCA].
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[[Category: Saccharomyces cerevisiae]]
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==Reference==
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<ref group="xtra">PMID:020659891</ref><references group="xtra"/><references/>
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[[Category: Atcc 18824]]
[[Category: Inagaki, F.]]
[[Category: Inagaki, F.]]
[[Category: Kumeta, H.]]
[[Category: Kumeta, H.]]

Revision as of 13:48, 12 March 2014

Template:STRUCTURE 2kzk

Contents

Solution structure of alpha-mannosidase binding domain of Atg34

Template:ABSTRACT PUBMED 20659891

Function

[ATG34_YEAST] Cargo-receptor protein involved in the cytoplasm to vacuole transport (Cvt) and in autophagy. Recognizes cargo proteins, such as AMS1 and delivers them to the pre-autophagosomal structure for eventual engulfment by the autophagosome and targeting to the vacuole.[1] [2]

About this Structure

2kzk is a 1 chain structure with sequence from Atcc 18824. Full experimental information is available from OCA.

Reference

  • Watanabe Y, Noda NN, Kumeta H, Suzuki K, Ohsumi Y, Inagaki F. Selective transport of alpha-mannosidase by autophagic pathways: structural basis for cargo recognition by Atg19 and Atg34. J Biol Chem. 2010 Sep 24;285(39):30026-33. Epub 2010 Jul 21. PMID:20659891 doi:http://dx.doi.org/10.1074/jbc.M110.143545
  1. ↑ Suzuki K, Kondo C, Morimoto M, Ohsumi Y. Selective transport of alpha-mannosidase by autophagic pathways: identification of a novel receptor, Atg34p. J Biol Chem. 2010 Sep 24;285(39):30019-25. doi: 10.1074/jbc.M110.143511. Epub, 2010 Jul 16. PMID:20639194 doi:http://dx.doi.org/10.1074/jbc.M110.143511
  2. ↑ Watanabe Y, Noda NN, Kumeta H, Suzuki K, Ohsumi Y, Inagaki F. Selective transport of alpha-mannosidase by autophagic pathways: structural basis for cargo recognition by Atg19 and Atg34. J Biol Chem. 2010 Sep 24;285(39):30026-33. Epub 2010 Jul 21. PMID:20659891 doi:http://dx.doi.org/10.1074/jbc.M110.143545

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