4bme

(Difference between revisions)

Revision as of 08:42, 19 March 2014

[LEG8_HUMAN] Lectin with a marked preference for 3'-O-sialylated and 3'-O-sulfated glycans.^[1]

4bme is a 2 chain structure. Full crystallographic information is available from OCA.

Ruiz FM, Scholz BA, Buzamet E, Kopitz J, Andre S, Menendez M, Romero A, Solis D, Gabius HJ. Natural single amino acid polymorphism (F19Y) in human galectin-8: detection of structural alterations and increased growth-regulatory activity on tumor cells. FEBS J. 2014 Mar;281(5):1446-64. doi: 10.1111/febs.12716. Epub 2014 Feb 3. PMID:24418318 doi:http://dx.doi.org/10.1111/febs.12716

↑ Ideo H, Matsuzaka T, Nonaka T, Seko A, Yamashita K. Galectin-8-N-domain recognition mechanism for sialylated and sulfated glycans. J Biol Chem. 2011 Apr 1;286(13):11346-55. Epub 2011 Feb 2. PMID:21288902 doi:10.1074/jbc.M110.195925

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-'''Unreleased structure'''
+{{STRUCTURE_4bme|  PDB=4bme  |  SCENE=  }}
+===Crystal structure of the N terminal domain of human Galectin 8, F19Y mutant===
+{{ABSTRACT_PUBMED_24418318}}
-The entry 4bme is ON HOLD  until Paper Publication
+==Function==
+[[http://www.uniprot.org/uniprot/LEG8_HUMAN LEG8_HUMAN]] Lectin with a marked preference for 3'-O-sialylated and 3'-O-sulfated glycans.<ref>PMID:21288902</ref>
-Authors: Buzamet, E., Ruiz, F.M., Menendez, M., Romero, A., Gabius, H.J., Solis, D.
+==About this Structure==
+[[4bme]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BME OCA].
-Description: Crystal structure of the N terminal domain of human Galectin 8, F19Y mutant
+==Reference==
+<ref group="xtra">PMID:024418318</ref><references group="xtra"/><references/>
+[[Category: Buzamet, E.]]
+[[Category: Gabius, H J.]]
+[[Category: Menendez, M.]]
+[[Category: Romero, A.]]
+[[Category: Ruiz, F M.]]
+[[Category: Solis, D.]]
+[[Category: Carbohydrate recognition]]
+[[Category: Sugar binding protein]]