4hog

(Difference between revisions)

Revision as of 08:57, 19 March 2014

4hog is a 2 chain structure. Full crystallographic information is available from OCA.

G-Dayanandan N, Paulsen JL, Viswanathan K, Keshipeddy S, Lombardo MN, Zhou W, Lamb KM, Sochia AE, Alverson JB, Priestley ND, Wright DL, Anderson AC. Propargyl-Linked Antifolates are Dual Inhibitors of Candida albicans and Candida glabrata. J Med Chem. 2014 Mar 6. PMID:24568657 doi:http://dx.doi.org/10.1021/jm401916j

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-'''Unreleased structure'''
+{{STRUCTURE_4hog|  PDB=4hog  |  SCENE=  }}
+===Candida glabrata dihydrofolate reductase complexed with NADPH and 5-[3-(2-methoxy-4-phenylphenyl)but-1-yn-1-yl]-6-methylpyrimidine-2,4-diamine (UCP111H)===
+{{ABSTRACT_PUBMED_24568657}}
-The entry 4hog is ON HOLD  until Mar 15 2015
+==About this Structure==
+[[4hog]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HOG OCA].
-Authors: Paulsen, J.L., Anderson, A.C.
+==Reference==
+<ref group="xtra">PMID:024568657</ref><references group="xtra"/><references/>
-Description: Candida glabrata dihydrofolate reductase complexed with NADPH and 5-[3-(2-methoxy-4-phenylphenyl)but-1-yn-1-yl]-6-methylpyrimidine-2,4-diamine (UCP111H)
+[[Category: Anderson, A C.]]
+[[Category: Paulsen, J L.]]
+[[Category: Antifungal agent]]
+[[Category: Candida glabrata]]
+[[Category: Drug design]]
+[[Category: Enzyme inhibitor]]
+[[Category: Fungal protein]]
+[[Category: Oxidoreductase-oxidoreductase inhibitor complex]]
+[[Category: Structure-activity relationship]]
+[[Category: Tetrahydrofolate dehydrogenase]]