4mb8

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{{STRUCTURE_4mb8| PDB=4mb8 | SCENE= }}
{{STRUCTURE_4mb8| PDB=4mb8 | SCENE= }}
===Evolutionary history and metabolic insights of ancient mammalian uricases===
===Evolutionary history and metabolic insights of ancient mammalian uricases===
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{{ABSTRACT_PUBMED_24550457}}
==Function==
==Function==
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==About this Structure==
==About this Structure==
[[4mb8]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MB8 OCA].
[[4mb8]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MB8 OCA].
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==Reference==
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<ref group="xtra">PMID:024550457</ref><references group="xtra"/><references/>
[[Category: Factor independent urate hydroxylase]]
[[Category: Factor independent urate hydroxylase]]
[[Category: Murphy, M N.]]
[[Category: Murphy, M N.]]

Revision as of 09:06, 19 March 2014

Template:STRUCTURE 4mb8

Contents

Evolutionary history and metabolic insights of ancient mammalian uricases

Template:ABSTRACT PUBMED 24550457

Function

[URIC_CANFA] Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin.

About this Structure

4mb8 is a 4 chain structure. Full crystallographic information is available from OCA.

Reference

  • Kratzer JT, Lanaspa MA, Murphy MN, Cicerchi C, Graves CL, Tipton PA, Ortlund EA, Johnson RJ, Gaucher EA. Evolutionary history and metabolic insights of ancient mammalian uricases. Proc Natl Acad Sci U S A. 2014 Mar 11;111(10):3763-8. doi:, 10.1073/pnas.1320393111. Epub 2014 Feb 18. PMID:24550457 doi:http://dx.doi.org/10.1073/pnas.1320393111

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