4i14

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{{STRUCTURE_4i14| PDB=4i14 | SCENE= }}
{{STRUCTURE_4i14| PDB=4i14 | SCENE= }}
===Crystal Structure of Mtb-ribA2 (Rv1415)===
===Crystal Structure of Mtb-ribA2 (Rv1415)===
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{{ABSTRACT_PUBMED_23999287}}
==Function==
==Function==
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==About this Structure==
==About this Structure==
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[[4i14]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_h37ra Mycobacterium tuberculosis h37ra]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4I14 OCA].
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[[4i14]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycta Mycta]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4I14 OCA].
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[[Category: Mycobacterium tuberculosis h37ra]]
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==Reference==
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<ref group="xtra">PMID:023999287</ref><references group="xtra"/><references/>
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[[Category: Mycta]]
[[Category: Gautam, R.]]
[[Category: Gautam, R.]]
[[Category: Karthikeyan, S.]]
[[Category: Karthikeyan, S.]]

Revision as of 09:09, 19 March 2014

Template:STRUCTURE 4i14

Contents

Crystal Structure of Mtb-ribA2 (Rv1415)

Template:ABSTRACT PUBMED 23999287

Function

[RIBBA_MYCTA] Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity). Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity).

About this Structure

4i14 is a 2 chain structure with sequence from Mycta. Full crystallographic information is available from OCA.

Reference

  • Singh M, Kumar P, Yadav S, Gautam R, Sharma N, Karthikeyan S. The crystal structure reveals the molecular mechanism of bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II (Rv1415) from Mycobacterium tuberculosis. Acta Crystallogr D Biol Crystallogr. 2013 Sep;69(Pt 9):1633-44. doi:, 10.1107/S0907444913011402. Epub 2013 Aug 15. PMID:23999287 doi:http://dx.doi.org/10.1107/S0907444913011402

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