3cbk

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[[Image:3cbk.png|left|200px]]
 
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{{STRUCTURE_3cbk| PDB=3cbk | SCENE= }}
{{STRUCTURE_3cbk| PDB=3cbk | SCENE= }}
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===chagasin-cathepsin B===
===chagasin-cathepsin B===
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{{ABSTRACT_PUBMED_18515357}}
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{{ABSTRACT_PUBMED_018515357}}
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==Function==
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[[http://www.uniprot.org/uniprot/CATB_HUMAN CATB_HUMAN]] Thiol protease which is believed to participate in intracellular degradation and turnover of proteins. Has also been implicated in tumor invasion and metastasis.
==About this Structure==
==About this Structure==
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[[3cbk]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [http://en.wikipedia.org/wiki/Trypanosoma_cruzi Trypanosoma cruzi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CBK OCA].
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[[3cbk]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CBK OCA].
==See Also==
==See Also==
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==Reference==
==Reference==
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<ref group="xtra">PMID:018515357</ref><references group="xtra"/>
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<ref group="xtra">PMID:018515357</ref><references group="xtra"/><references/>
[[Category: Cathepsin B]]
[[Category: Cathepsin B]]
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[[Category: Homo sapiens]]
 
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[[Category: Trypanosoma cruzi]]
 
[[Category: Abrahamson, M.]]
[[Category: Abrahamson, M.]]
[[Category: Bujacz, G D.]]
[[Category: Bujacz, G D.]]

Revision as of 09:14, 19 March 2014

Template:STRUCTURE 3cbk

Contents

chagasin-cathepsin B

Template:ABSTRACT PUBMED 18515357

Function

[CATB_HUMAN] Thiol protease which is believed to participate in intracellular degradation and turnover of proteins. Has also been implicated in tumor invasion and metastasis.

About this Structure

3cbk is a 2 chain structure. Full crystallographic information is available from OCA.

See Also

Reference

  • Redzynia I, Ljunggren A, Abrahamson M, Mort JS, Krupa JC, Jaskolski M, Bujacz G. Displacement of the occluding loop by the parasite protein, chagasin, results in efficient inhibition of human cathepsin B. J Biol Chem. 2008 Aug 15;283(33):22815-25. Epub 2008 May 30. PMID:18515357 doi:10.1074/jbc.M802064200

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