4j1s
From Proteopedia
(Difference between revisions)
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| - | + | {{STRUCTURE_4j1s| PDB=4j1s | SCENE= }} | |
| + | ===Crystal structure of a ketoreductase domain from the bacillaene assembly line=== | ||
| - | + | ==Function== | |
| + | [[http://www.uniprot.org/uniprot/PKSJ_BACSU PKSJ_BACSU]] Involved in some intermediate steps for the synthesis of the antibiotic polyketide bacillaene which is involved in secondary metabolism.<ref>PMID:16460000</ref> <ref>PMID:17234808</ref> | ||
| - | + | ==About this Structure== | |
| + | [[4j1s]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4J1S OCA]. | ||
| - | + | ==Reference== | |
| + | <references group="xtra"/><references/> | ||
| + | [[Category: Keatinge-Clay, A T.]] | ||
| + | [[Category: Zheng, J.]] | ||
| + | [[Category: Ketoreductase]] | ||
| + | [[Category: Oxidoreductase]] | ||
| + | [[Category: Rossmann fold]] | ||
Revision as of 09:30, 19 March 2014
Contents |
Crystal structure of a ketoreductase domain from the bacillaene assembly line
Function
[PKSJ_BACSU] Involved in some intermediate steps for the synthesis of the antibiotic polyketide bacillaene which is involved in secondary metabolism.[1] [2]
About this Structure
4j1s is a 1 chain structure. Full crystallographic information is available from OCA.
Reference
- ↑ Dorrestein PC, Blackhall J, Straight PD, Fischbach MA, Garneau-Tsodikova S, Edwards DJ, McLaughlin S, Lin M, Gerwick WH, Kolter R, Walsh CT, Kelleher NL. Activity screening of carrier domains within nonribosomal peptide synthetases using complex substrate mixtures and large molecule mass spectrometry. Biochemistry. 2006 Feb 14;45(6):1537-46. PMID:16460000 doi:http://dx.doi.org/10.1021/bi052333k
- ↑ Butcher RA, Schroeder FC, Fischbach MA, Straight PD, Kolter R, Walsh CT, Clardy J. The identification of bacillaene, the product of the PksX megacomplex in Bacillus subtilis. Proc Natl Acad Sci U S A. 2007 Jan 30;104(5):1506-9. Epub 2007 Jan 18. PMID:17234808 doi:http://dx.doi.org/10.1073/pnas.0610503104
