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4jbr

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'''Unreleased structure'''
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{{STRUCTURE_4jbr| PDB=4jbr | SCENE= }}
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===tRNA-guanine transglycosylase Y330C mutant as covalently linked dimer in space group P6(5)22===
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The entry 4jbr is ON HOLD until Paper Publication
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==Function==
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[[http://www.uniprot.org/uniprot/TGT_ZYMMO TGT_ZYMMO]] Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).[HAMAP-Rule:MF_00168]
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Authors: Jakobi, S., Klebe, G.
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==About this Structure==
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[[4jbr]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JBR OCA].
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Description: tRNA-guanine transglycosylase Y330C mutant as covalently linked dimer in space group P6(5)22
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[[Category: Jakobi, S.]]
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[[Category: Klebe, G.]]
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[[Category: Covalent dimer]]
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[[Category: Guanine]]
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[[Category: Preq1]]
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[[Category: Tim-barrel]]
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[[Category: Transferase]]
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[[Category: Trna]]

Revision as of 09:30, 19 March 2014

Template:STRUCTURE 4jbr

tRNA-guanine transglycosylase Y330C mutant as covalently linked dimer in space group P6(5)22

Function

[TGT_ZYMMO] Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).[HAMAP-Rule:MF_00168]

About this Structure

4jbr is a 1 chain structure. Full crystallographic information is available from OCA.

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OCA

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