5tln
From Proteopedia
(Difference between revisions)
(New page: 200px<br /><applet load="5tln" size="450" color="white" frame="true" align="right" spinBox="true" caption="5tln, resolution 2.3Å" /> '''BINDING OF HYDROXAMIC...) |
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| - | [[Image:5tln.gif|left|200px]]<br /><applet load="5tln" size=" | + | [[Image:5tln.gif|left|200px]]<br /><applet load="5tln" size="350" color="white" frame="true" align="right" spinBox="true" |
caption="5tln, resolution 2.3Å" /> | caption="5tln, resolution 2.3Å" /> | ||
'''BINDING OF HYDROXAMIC ACID INHIBITORS TO CRYSTALLINE THERMOLYSIN SUGGESTS A PENTACOORDINATE ZINC INTERMEDIATE IN CATALYSIS'''<br /> | '''BINDING OF HYDROXAMIC ACID INHIBITORS TO CRYSTALLINE THERMOLYSIN SUGGESTS A PENTACOORDINATE ZINC INTERMEDIATE IN CATALYSIS'''<br /> | ||
==About this Structure== | ==About this Structure== | ||
| - | 5TLN is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Bacillus_thermoproteolyticus Bacillus thermoproteolyticus] with CA, ZN and BAN as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Thermolysin Thermolysin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.24.27 3.4.24.27] Full crystallographic information is available from [http:// | + | 5TLN is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Bacillus_thermoproteolyticus Bacillus thermoproteolyticus] with <scene name='pdbligand=CA:'>CA</scene>, <scene name='pdbligand=ZN:'>ZN</scene> and <scene name='pdbligand=BAN:'>BAN</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Thermolysin Thermolysin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.24.27 3.4.24.27] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5TLN OCA]. |
==Reference== | ==Reference== | ||
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[[Category: Single protein]] | [[Category: Single protein]] | ||
[[Category: Thermolysin]] | [[Category: Thermolysin]] | ||
| - | [[Category: Holmes, M | + | [[Category: Holmes, M A.]] |
| - | [[Category: Matthews, B | + | [[Category: Matthews, B W.]] |
[[Category: BAN]] | [[Category: BAN]] | ||
[[Category: CA]] | [[Category: CA]] | ||
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[[Category: hydrolase (metalloproteinase)]] | [[Category: hydrolase (metalloproteinase)]] | ||
| - | ''Page seeded by [http:// | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 19:15:59 2008'' |
Revision as of 17:16, 21 February 2008
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BINDING OF HYDROXAMIC ACID INHIBITORS TO CRYSTALLINE THERMOLYSIN SUGGESTS A PENTACOORDINATE ZINC INTERMEDIATE IN CATALYSIS
About this Structure
5TLN is a Single protein structure of sequence from Bacillus thermoproteolyticus with , and as ligands. Active as Thermolysin, with EC number 3.4.24.27 Full crystallographic information is available from OCA.
Reference
Binding of hydroxamic acid inhibitors to crystalline thermolysin suggests a pentacoordinate zinc intermediate in catalysis., Holmes MA, Matthews BW, Biochemistry. 1981 Nov 24;20(24):6912-20. PMID:7317361
Page seeded by OCA on Thu Feb 21 19:15:59 2008
