4nn6

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
'''Unreleased structure'''
+
{{STRUCTURE_4nn6| PDB=4nn6 | SCENE= }}
 +
===Cytokine receptor complex - Crystal form 1B===
-
The entry 4nn6 is ON HOLD until Paper Publication
+
==Function==
 +
[[http://www.uniprot.org/uniprot/TSLP_MOUSE TSLP_MOUSE]] Cytokine that induces the release of T-cell-attracting chemokines from monocytes and, in particular, enhances the maturation of CD11c(+) dendritic cells. Can induce allergic inflammation by directly activating mast cells (By similarity). [[http://www.uniprot.org/uniprot/CRLF2_MOUSE CRLF2_MOUSE]] Receptor for thymic stromal lymphopoietin (TSLP). Forms a functional complex with TSLP and IL7R which is capable of stimulating cell proliferation through activation of STAT3 and STAT5. Also activates JAK2. Implicated in the development of the hematopoietic system. [[http://www.uniprot.org/uniprot/IL7RA_MOUSE IL7RA_MOUSE]] Receptor for interleukin-7. Also acts as a receptor for thymic stromal lymphopoietin (TSLP).
-
Authors: Verstraete, K., van Schie, L., Savvides, S.N.
+
==About this Structure==
-
 
+
[[4nn6]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NN6 OCA].
-
Description: Cytokine receptor complex -Crystal form 1B
+
[[Category: Savvides, S N.]]
 +
[[Category: Schie, L van.]]
 +
[[Category: Verstraete, K.]]
 +
[[Category: Cell surface]]
 +
[[Category: Chr domain]]
 +
[[Category: Cytokine-cytokine receptor complex]]
 +
[[Category: Four helical bundle fold]]
 +
[[Category: Tslp cytokine signaling]]
 +
[[Category: Tslpr and il-7ralpha receptor]]

Revision as of 09:40, 19 March 2014

Template:STRUCTURE 4nn6

Cytokine receptor complex - Crystal form 1B

Function

[TSLP_MOUSE] Cytokine that induces the release of T-cell-attracting chemokines from monocytes and, in particular, enhances the maturation of CD11c(+) dendritic cells. Can induce allergic inflammation by directly activating mast cells (By similarity). [CRLF2_MOUSE] Receptor for thymic stromal lymphopoietin (TSLP). Forms a functional complex with TSLP and IL7R which is capable of stimulating cell proliferation through activation of STAT3 and STAT5. Also activates JAK2. Implicated in the development of the hematopoietic system. [IL7RA_MOUSE] Receptor for interleukin-7. Also acts as a receptor for thymic stromal lymphopoietin (TSLP).

About this Structure

4nn6 is a 3 chain structure. Full crystallographic information is available from OCA.

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/4nn6"
Personal tools