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4mwi
From Proteopedia
(Difference between revisions)
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==About this Structure== | ==About this Structure== | ||
| - | [[4mwi]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MWI OCA]. | + | [[4mwi]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MWI OCA]. |
==Reference== | ==Reference== | ||
<ref group="xtra">PMID:024219132</ref><references group="xtra"/><references/> | <ref group="xtra">PMID:024219132</ref><references group="xtra"/><references/> | ||
| + | [[Category: Human]] | ||
[[Category: Czabotar, P E.]] | [[Category: Czabotar, P E.]] | ||
[[Category: Murphy, J M.]] | [[Category: Murphy, J M.]] | ||
Revision as of 09:59, 19 March 2014
Contents |
Crystal structure of the human MLKL pseudokinase domain
Template:ABSTRACT PUBMED 24219132
Function
[MLKL_HUMAN] Required for the execution of programmed necrosis.[1]
About this Structure
4mwi is a 1 chain structure with sequence from Human. Full crystallographic information is available from OCA.
Reference
- Murphy JM, Lucet IS, Hildebrand JM, Tanzer MC, Young SN, Sharma P, Lessene G, Alexander WS, Babon JJ, Silke J, Czabotar PE. Insights into the evolution of divergent nucleotide-binding mechanisms among pseudokinases revealed by crystal structures of human and mouse MLKL. Biochem J. 2013 Nov 13. PMID:24219132 doi:http://dx.doi.org/10.1042/BJ20131270
- ↑ Wang Z, Jiang H, Chen S, Du F, Wang X. The mitochondrial phosphatase PGAM5 functions at the convergence point of multiple necrotic death pathways. Cell. 2012 Jan 20;148(1-2):228-43. doi: 10.1016/j.cell.2011.11.030. PMID:22265414 doi:http://dx.doi.org/10.1016/j.cell.2011.11.030
