Luciferase
From Proteopedia
(Difference between revisions)
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== 3D Structures of Luciferase == | == 3D Structures of Luciferase == | ||
| - | + | Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} | |
[[3iep]], [[1lci]] – fLuc – firefly<br /> | [[3iep]], [[1lci]] – fLuc – firefly<br /> | ||
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[[2d1r]] - LcLuc (mutant)+oxyluciferin+AMP<br /> | [[2d1r]] - LcLuc (mutant)+oxyluciferin+AMP<br /> | ||
[[2d1s]], [[2d1t]] - LcLuc (mutant)+intermediate analog<br /> | [[2d1s]], [[2d1t]] - LcLuc (mutant)+intermediate analog<br /> | ||
| - | [[3qya]] – | + | [[3qya]] – LtLuc (mutant) – ''Lampyris turkestanicus''<br /> |
| + | [[4m46]] – LtLuc<br /> | ||
[[3fgc]] – VhLuc α+β chain+FMN – ''Vibrio harveyi''<br /> | [[3fgc]] – VhLuc α+β chain+FMN – ''Vibrio harveyi''<br /> | ||
[[1luc]], [[1brl]] - VhLuc α+β chain<br /> | [[1luc]], [[1brl]] - VhLuc α+β chain<br /> | ||
Revision as of 09:11, 23 March 2014
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References
- ↑ Auld DS, Lovell S, Thorne N, Lea WA, Maloney DJ, Shen M, Rai G, Battaile KP, Thomas CJ, Simeonov A, Hanzlik RP, Inglese J. Molecular basis for the high-affinity binding and stabilization of firefly luciferase by PTC124. Proc Natl Acad Sci U S A. 2010 Mar 16;107(11):4878-83. Epub 2010 Mar 1. PMID:20194791
- ↑ Campbell ZT, Weichsel A, Montfort WR, Baldwin TO. Crystal Structure of the Bacterial Luciferase:Flavin Complex Provides Insight into the Function of the subunit. Biochemistry. 2009 May 12. PMID:19435287 doi:http://dx.doi.org/10.1021/bi900003t
Additional Literature
- Marques SM, Esteves da Silva JC. Firefly bioluminescence: a mechanistic approach of luciferase catalyzed reactions. IUBMB Life. 2009 Jan;61(1):6-17. PMID:18949818 doi:10.1002/iub.134
- Inouye S. Firefly luciferase: an adenylate-forming enzyme for multicatalytic functions. Cell Mol Life Sci. 2010 Feb;67(3):387-404. Epub 2009 Oct 27. PMID:19859663 doi:10.1007/s00018-009-0170-8
External Resources
- Yahoo news coverage of luciferase studies funded research for military applications
- Luciferase at Wikipedia
- Luciferase: June 2006 Molecule of the Month as part of the series of tutorials that are at the RCSB Protein Data Bank and written by David S. Goodsell
Proteopedia Page Contributors and Editors (what is this?)
Michal Harel, Wayne Decatur, Alexander Berchansky, Loïc Gazquez, Charlene Planchenault, David Canner
