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MDM4
From Proteopedia
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== 3D Structures of MDM4 == | == 3D Structures of MDM4 == | ||
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| + | Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} | ||
[[2cr8]] – hMDM4 ZF-RNBP domain – NMR<br /> | [[2cr8]] – hMDM4 ZF-RNBP domain – NMR<br /> | ||
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[[3fdo]], [[3jzo]], [[3jzp]], [[3jzq]], [[3jzr]], [[3jzs]] – hMDM4 p53-binding domain + peptide<br /> | [[3fdo]], [[3jzo]], [[3jzp]], [[3jzq]], [[3jzr]], [[3jzs]] – hMDM4 p53-binding domain + peptide<br /> | ||
[[3lbj]] - hMDM4 p53-binding domain + inhibitor<br /> | [[3lbj]] - hMDM4 p53-binding domain + inhibitor<br /> | ||
| + | [[3u15]] - hMDM4 p53-binding domain + indolyl hydantoin<br /> | ||
[[3dac]] – hMDM4 (mutant) + p53 transactivation domain<br /> | [[3dac]] – hMDM4 (mutant) + p53 transactivation domain<br /> | ||
[[2vyr]] – hMDM4 N terminal + antibody<br /> | [[2vyr]] – hMDM4 N terminal + antibody<br /> | ||
[[3fe7]], [[3fea]], [[3eqy]] - hMDM4 N terminal (mutant) + peptide<br /> | [[3fe7]], [[3fea]], [[3eqy]] - hMDM4 N terminal (mutant) + peptide<br /> | ||
[[2vje]], [[2vjf]] – hMDM2 residues 383-446 + hMDM4 residues 428-490<br /> | [[2vje]], [[2vjf]] – hMDM2 residues 383-446 + hMDM4 residues 428-490<br /> | ||
| + | [[2z5s]] - zMDM4 SWIB domain + p53 transactivation domain – zebrafish<br /> | ||
| + | [[2z5t]] - zMDM4 SWIB domain (mutant) + p53 transactivation domain <br /> | ||
| + | [[4n5t]] - zMDM4 SWIB domain (mutant) + stapled peptide <br /> | ||
[[Category:Topic Page]] | [[Category:Topic Page]] | ||
Revision as of 10:41, 25 March 2014
MDM4 is a 490 amino acid protein containing a RING finger domain and a nuclear localization signal. MDM4 interacts with protein MDM2. Both of these proteins show structure similarity and contain a p53-binding domain in their N terminal.
Contents |
3D Structures of MDM4
Updated on 25-March-2014
2cr8 – hMDM4 ZF-RNBP domain – NMR
3dab – hMDM4 + p53 transactivation domain
3fdo, 3jzo, 3jzp, 3jzq, 3jzr, 3jzs – hMDM4 p53-binding domain + peptide
3lbj - hMDM4 p53-binding domain + inhibitor
3u15 - hMDM4 p53-binding domain + indolyl hydantoin
3dac – hMDM4 (mutant) + p53 transactivation domain
2vyr – hMDM4 N terminal + antibody
3fe7, 3fea, 3eqy - hMDM4 N terminal (mutant) + peptide
2vje, 2vjf – hMDM2 residues 383-446 + hMDM4 residues 428-490
2z5s - zMDM4 SWIB domain + p53 transactivation domain – zebrafish
2z5t - zMDM4 SWIB domain (mutant) + p53 transactivation domain
4n5t - zMDM4 SWIB domain (mutant) + stapled peptide
