4jwc
From Proteopedia
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==About this Structure== | ==About this Structure== | ||
| - | [[4jwc]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JWC OCA]. | + | [[4jwc]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JWC OCA]. |
==Reference== | ==Reference== | ||
<ref group="xtra">PMID:024164259</ref><references group="xtra"/><references/> | <ref group="xtra">PMID:024164259</ref><references group="xtra"/><references/> | ||
| + | [[Category: Ecoli]] | ||
[[Category: Straeter, N.]] | [[Category: Straeter, N.]] | ||
[[Category: Zahn, M.]] | [[Category: Zahn, M.]] | ||
Revision as of 06:16, 26 March 2014
Contents |
Crystal structure of the substrate binding domain of E.coli DnaK in complex with bovine Bac7(1-16)
Template:ABSTRACT PUBMED 24164259
Function
[DNAK_ECOLI] Plays an essential role in the initiation of phage lambda DNA replication, where it acts in an ATP-dependent fashion with the DnaJ protein to release lambda O and P proteins from the preprimosomal complex. DnaK is also involved in chromosomal DNA replication, possibly through an analogous interaction with the DnaA protein. Also participates actively in the response to hyperosmotic shock.[HAMAP-Rule:MF_00332] [CTHL3_BOVIN] Exerts, in vitro, a potent antimicrobial activity. Probably due to an impairment of the function of the respiratory chain and of energy-dependent activities in the inner membrane of susceptible microorganisms.
About this Structure
4jwc is a 4 chain structure with sequence from Ecoli. Full crystallographic information is available from OCA.
Reference
- Zahn M, Kieslich B, Berthold N, Knappe D, Hoffmann R, Strater N. Structural Identification of DnaK Binding Sites Within Bovine and Sheep Bactenecin Bac7. Protein Pept Lett. 2013 Oct 25. PMID:24164259
