Mitogen-activated protein kinase

From Proteopedia

(Difference between revisions)

Revision as of 11:41, 27 March 2014

Crystal Structure of the Mitogen-activated protein kinase, 1erk

Mitogen-activated protein kinase (MAPK) also known as Extracellular Signal-Regulated Kinase (ERK) are serine/threonine kinases which regulate various cellular activities in response to extracellular stimuli by mitogens, heat shock and more. MAPK is part of the MAPK cascade which consists of MAPK, MAP2K and MAP3K which are activated by phosphorylation. MAPK1 and MAPK3 are activated in response to growth factors. For MAPK2 representations see Michael Roberts/BIOL115/ERK2. MAPK6 is activated by phorbol esters. MAPK7 is activated by stress stimuli. MAPK8, MAPK9, MAPK10 (called also c-Jun N-terminal kinase 3 or JNK3), MAPK11, MAPK12, MAPK13, MAPK14 are stress-activated. MAPK11 (also called p38-β MAPK), MAPK12 (also called p38-γ MAPK), MAPK13 (also called p38-δ MAPK), MAPK14(also called p38-α MAPK) belong to the class called p38 MAPK. images on the left and right correspond to one representative MAPK structure, i.e. the rat MAPK1 (1erk).

1 3D Structures of Mitogen-activated protein kinase
- 1.1 MAPK1
- 1.2 MAPK2
- 1.3 MAPK3
- 1.4 MAPK6
- 1.5 MAPK7
- 1.6 MAPK8
- 1.7 MAPK9
- 1.8 MAPK10
- 1.9 MAPK11
- 1.10 MAPK13
- 1.11 MAPK14
- 1.12 MAPK FUSS

3D Structures of Mitogen-activated protein kinase

Updated on 27-March-2014

MAPK1

4g6n, 4g6o, 4gsb – hMAPK1 - human
3i5z, 3i60, 2e14, 2ojg, 2oji, 2ojj, 1wzy, 1tvo, 3sa0, 4fux, 4fuy, 4fv0, 4fv1, 4fv2, 4fv3, 4fv4, 4fv5, 4fv6, 4fv7, 4fv8, 4fv9 – hMAPK1+inhibitor - human
2y9q – hMAPK1 + MAP kinase-interacting Ser/Thr protein kinase peptide
3tei – hMAPK1 (mutant) + ribosomal protein S6 kinase α-1
4iz5, 4iz7, 4iza – hMAPK1 (mutant) + astrocytic phosphoprotein
4fmq – hMAPK1 + MAPK docking peptide
4h3q – hMAPK1 + MAP2K 2 peptide
2z7l, 3c9w, 3qyw, 3qyz, 3qyi - rMAPK1+inhibitor – rat
1erk - rMAPK1
1gol, 3r63 - rMAPK1 (mutant)
2gph - rMAPK1 (mutant)+HEPTP (mutant)
3o71 - rMAPK1 + colorectal cancer peptide
2fys - rMAPK1 + KIM peptide
4gt3, 4gva – rMAPK1 + nucleotide
4i5h – rMAPK1 (mutant) + inhibitor
3o71 - rMAPK1 + colorectal cancer peptide
3zu7, 3zuv – rMAPK1 + ankyrin repeat protein
2y4i – raMAPK1+kinase suppressor of RAS 2 – rabbit
3oz6 - MAPK1 - Cryptosporidium parvum

MAPK2

3gok - hMAPK2 kinase domain
2pzy, 2p3g, 2jbo, 2jbp – hMAPK2+inhibitor
3a2c, 3kc3, 3fpm, 3fyj, 3fyk - hMAPK2 kinase domain +inhibitor
3m2w, 3kga, 3ka0 – hMAPK2 kinase domain (mutant)+inhibitor
2oza, 2okr, 2onl – hMAPK2+ hMAPK14
2npt - hMAPK2+ hMAPK5
2erk – rMAPK2
3erk, 4erk – rMAPK2+inhibitor

MAPK3

2zoq – hMAPK3

MAPK6

3fxw, 3fhr – hMAPK3 kinase domain +inhibitor
2i6l – hMAPK6

MAPK7

4ic8 – hMAPK7
4b99 – hMAPK7+inhibitor
4ic7 – hMAPK7+ MAP2K 5

MAPK8

3o17, 2gmx, 2g01, 3vud, 3vug, 3vuh, 3vui, 3vuk, 3vul, 3vum – hMAPK8 (mutant)+JIP1 peptide
1ukh, 1uki - jMAPK8 JNK1+JIP1 peptide
3v3v - hMAPK8 JNK1+JIP1 peptide + quercedagetin
3o2m - hMAPK8 (mutant)+JIP1 peptide+biaryl tetrazole
2xrw, 2xs0 - hMAPK8 + NFAT peptide
3elj, 3pze, 4awi, 4l7f - hMAPK8+inhibitor
4e73, 4g1w, 4hys, 4hyu, 4izy – hMAPK8 + JIP1 +inhibitor
2no3, 2h96 – hMAPK8 (mutant)+inhibitor

MAPK9

3e7o - hMAPK9 (mutant)
3npc – hMAPK9 (mutant)+inhibitor

MAPK10

3kvx, 3fv8, 2waj, 3fi2, 3fi3, 3da6, 2zdt, 2zdu, 3cgf, 3cgo, 2r9s, 2o0u, 2o2u, 2exc, 2b1p, 1pmn, 1pmq, 1pmu, 1pmv, 3oy1, 2ok1, 3ttj, 3tti, 3rtp, 3v6r, 3v6s – hMAPK10+inhibitor
3ptg, 4h39 - hMAPK10 catalytic domain + JIP1 peptide
4h36 – hMAPK10 catalytic domain + ATF2 peptide
4h3b – hMAPK10 catalytic domain + SAB peptide
1jnk – hMAPK10 catalytic domain + AMPPNP
3g9l, 3g90, 3g9n, 2p33 – hMAPK10 catalytic domain+inhibitor
3oxi - hMAPK10 + MAPK8 interacting protein + inhibitor

MAPK11

3gp0 – hMAPK11+inhibitor
3gc8, 3gc9 – hMAPK11 (mutant)+inhibitor

MAPK13

3coi, 4exu – hMAPK13
4eyj, 4eym - hMAPK13 +inhibitor

MAPK14

3mgy, 3mh0, 3mh1, 3mh2, 3mh3, 3hvc, 3npq, 1wbo, 1r39, 2npq, 1wfc, 1cm8 – hMAPK14
2lgc – hMAPK14 – NMR
3od6, 3ody, 3odz, 3oef, 3p4k, 2fsl, 2fsm, 2fso, 2fst, 1r3c, 4e5a, 4geo – hMAPK14 (mutant)
3new, 3ocg, 3mvl, 3mvm, 3nnu, 3nnv, 3nnw, 3nnx, 3nww, 3mpt, 3lhj, 3huc, 3itz, 3l8x, 3kf7, 3fi4, 3fkl, 3fkn, 3fko, 3fl4, 3fln, 3flq, 3fls, 3flw, 3fly, 3flz, 3fmh, 3fmj, 3fmk, 3fml, 3flm, 3fln, 3fsf, 3fsk, 3kq7, 3iph, 3hv4, 3hv5, 3hv6, 3hv7, 3k3i, 3hec, 3heg, 3gi3, 3hp2, 3hp5, 3hrb, 3ha8, 3gfe, 3hl7, 3hll, 3gcu, 3fc1, 3dt1, 3e92, 3e93, 3d7z, 3d83, 3ctq, 2puu, 3bx5, 3c5u, 2zaz, 2zb0, 2zb1, 2qd9, 2ewa, 2gfs, 2baj, 2bak, 2bal, 2baq, 1zyj, 1wbn, 1wbs, 1wbt, 1wbv, 1wbw, 1zz2, 1zzl, 1yqj, 1w7h, 1w82, 1w83, 1w84, 1oz1, 1ouk, 1ouy, 1m7q, 1kv1, 1kv2, 1di9, 2rg5, 2rg6, 3bv3, 3bv2, 3fmm, 3fmn, 3lfa, 3mw1, 3pg3, 3roc ,2yis, 2yiw, 2yix, 3qud, 3que, 3rin, 3s3i, 3s4q, 3u8w, 3uvp, 3uvq, 3uvr, 3zs5, 3zsg, 3zsh, 3zsi, 3zya, 4a9y, 4aa0, 4aa4, 4aa5, 4aac, 4dli, 4dlj, 4e5b, 4eh2, 4eh3, 4eh4, 4eh5, 4eh6, 4eh7, 4eh8, 4eh9, 4ehv, 4ewq, 4f9w, 4f9y, 4fa2, 4kin, 4kip, 4kiq, 4l8m - hMAPK14+inhibitor
4e6a, 4e6c, 4e8a - hMAPK14+ lipid
3o8t, 3mpa, 3obg, 3o8u, 3o8p, 3obj, 3oc1, 3hub, 3l8s, 3hv3, 3iw5, 3iw6, 3iw7, 3iw8, 3k3j, 3gc7, 3gcp, 3gcq, 3gcs, 3gcv, 3ds6, 2i0h, 1ove, 3lfb, 3lfc, 3lfd, 3lfe, 3lff, 1bl6, 1bl7, 1bmk, 1a9u, 1ian - hMAPK14 (mutant)+inhibitor
2y8o – hMAPK14 (mutant) + dual specificity MAP2K peptide
4ka3, 4loo, 4lop, 4loq – hMAPK14 + docking peptide
3tg1 – hMAPK14 + MAPK phosphatase 5
2gtn, 2gtm, 3p5k, 3p78, 3p79, 3p7a, 3p7b, 3p7c - mMAPK14+inhibitor
2ghm, 2ghl, 1ywr - mMAPK14 (mutant)+inhibitor
3py3 - mMAPK14 phosphorylated
1yw2, 1p38 - mMAPK14 (mutant)
1lew - mMAPK14+MEF2A
1lez - mMAPK14+MKK3B

MAPK FUSS

2f9g, 2b9f – yMAPK FUSS – yeast
2fa2 – yMAPK FUSS (mutant)
2f49 - yMAPK FUSS+STE5 peptide
2b9h, 2b9i - yMAPK FUSS (mutant)+MSG5 peptide
2b9j - yMAPK FUSS (mutant)+FAR1 peptide

3rp9 – MAPK – Toxoplasma gondii
3uib – MAPK + inhibitor – Leishmania major

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky, Joel L. Sussman

Retrieved from "http://52.214.119.220/wiki/index.php/Mitogen-activated_protein_kinase"

Category: Topic Page

@@ Line 34: / Line 34: @@
-[[Mitogen-activated protein kinase]] (MAPK) also known as Extracellular Signal-Regulated Kinase (ERK) are serine/threonine kinases which regulate various cellular activities in response to extracellular stimuli by mitogens, heat shock and more.  MAPK is part of the MAPK cascade which consists of MAPK, [[Mitogen-activated protein kinase kinase|MAP2K]] and [[Mitogen-activated protein kinase kinase kinase|MAP3K]] which are activated by phosphorylation.  MAPK1 and MAPK3 are activated in response to growth factors. For MAPK2 representations see [[Michael Roberts/BIOL115/ERK2]].  MAPK6 is activated by phorbol esters.  MAPK7 is activated by stress stimuli.  MAPK8, MAPK9, MAPK10 (called also c-Jun N-terminal kinase 3 or JNK3), MAPK11, MAPK12, MAPK13, MAPK14 are stress-activated. MAPK11, MAPK12, MAPK13, MAPK14 belong to the class called p38 MAPK.   images on the left and right  correspond to one representative MAPK structure, ''i.e.'' the rat MAPK1 ([[1erk]]).
+[[Mitogen-activated protein kinase]] (MAPK) also known as Extracellular Signal-Regulated Kinase (ERK) are serine/threonine kinases which regulate various cellular activities in response to extracellular stimuli by mitogens, heat shock and more.  MAPK is part of the MAPK cascade which consists of MAPK, [[Mitogen-activated protein kinase kinase|MAP2K]] and [[Mitogen-activated protein kinase kinase kinase|MAP3K]] which are activated by phosphorylation.  MAPK1 and MAPK3 are activated in response to growth factors. For MAPK2 representations see [[Michael Roberts/BIOL115/ERK2]].  MAPK6 is activated by phorbol esters.  MAPK7 is activated by stress stimuli.  MAPK8, MAPK9, MAPK10 (called also c-Jun N-terminal kinase 3 or JNK3), MAPK11, MAPK12, MAPK13, MAPK14 are stress-activated. MAPK11 (also called p38-β MAPK),  MAPK12 (also called p38-γ MAPK),  MAPK13 (also called p38-δ MAPK),  MAPK14(also called p38-α MAPK) belong to the class called p38 MAPK.   images on the left and right  correspond to one representative MAPK structure, ''i.e.'' the rat MAPK1 ([[1erk]]).
 {{TOC limit|limit=2}}
@@ Line 47: / Line 47: @@
 Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
 ===MAPK1===
-[[3i5z]], [[3i60]], [[2e14]], [[2ojg]], [[2oji]], [[2ojj]], [[1wzy]], [[1tvo]] – hMAPK1+inhibitor - human<br />
+[[4g6n]], [[4g6o]], [[4gsb]] – hMAPK1 - human<br />
-[[2z7l]], [[3c9w]], [[3qyw]], [[3qyz]] - rMAPK1+inhibitor – rat<br />
+[[3i5z]], [[3i60]], [[2e14]], [[2ojg]], [[2oji]], [[2ojj]], [[1wzy]], [[1tvo]], [[3sa0]], [[4fux]], [[4fuy]], [[4fv0]], [[4fv1]], [[4fv2]], [[4fv3]], [[4fv4]], [[4fv5]], [[4fv6]], [[4fv7]], [[4fv8]], [[4fv9]] – hMAPK1+inhibitor - human<br />
+[[2y9q]] – hMAPK1 + MAP kinase-interacting Ser/Thr protein kinase peptide<br />
+[[3tei]] – hMAPK1 (mutant) + ribosomal protein S6 kinase α-1<br />
+[[4iz5]], [[4iz7]], [[4iza]] – hMAPK1 (mutant) + astrocytic phosphoprotein <br />
+[[4fmq]] – hMAPK1 + MAPK docking peptide<br />
+[[4h3q]] – hMAPK1 + MAP2K 2 peptide<br />
+[[2z7l]], [[3c9w]], [[3qyw]], [[3qyz]], [[3qyi]] - rMAPK1+inhibitor – rat<br />
 [[1erk]] - rMAPK1<br />
 [[1gol]], [[3r63]] - rMAPK1 (mutant)<br />
@@ Line 55: / Line 61: @@
 [[3o71]] - rMAPK1 + colorectal cancer peptide<br />
 [[2fys]] - rMAPK1 + KIM peptide<br />
+[[4gt3]], [[4gva]] – rMAPK1 + nucleotide<br />
+[[4i5h]] – rMAPK1 (mutant) + inhibitor<br />
+[[3o71]] - rMAPK1 + colorectal cancer peptide<br />
+[[3zu7]], [[3zuv]] – rMAPK1 + ankyrin repeat protein<br />
 [[2y4i]] – raMAPK1+kinase suppressor of RAS 2 – rabbit<br />
-[[3oz6]] - MAPK1 - Cryptosporidium parvum
+[[3oz6]] - MAPK1 - ''Cryptosporidium parvum''
 ===MAPK2===
@@ Line 80: / Line 89: @@
 ===MAPK7===
-[[2q8y]] - MAPK7+Virulence protein
+[[4ic8]] – hMAPK7<br />
+[[4b99]] – hMAPK7+inhibitor<br />
+[[4ic7]] – hMAPK7+ MAP2K 5<br />
 ===MAPK8===
-[[3o17]], [[2gmx]], [[2g01]] – hMAPK8 (mutant)+JIP1 peptide<br />
+[[3o17]], [[2gmx]], [[2g01]], [[3vud]], [[3vug]], [[3vuh]], [[3vui]], [[3vuk]], [[3vul]], [[3vum]] – hMAPK8 (mutant)+JIP1 peptide<br />
 [[1ukh]], [[1uki]] - jMAPK8 JNK1+JIP1 peptide<br />
+[[3v3v]] - hMAPK8 JNK1+JIP1 peptide + quercedagetin<br />
 [[3o2m]] - hMAPK8 (mutant)+JIP1 peptide+biaryl tetrazole<br />
 [[2xrw]], [[2xs0]] - hMAPK8 + NFAT peptide<br />
-[[3elj]] - hMAPK8+inhibitor<br />
+[[3elj]], [[3pze]], [[4awi]], [[4l7f]] - hMAPK8+inhibitor<br />
+[[4e73]], [[4g1w]], [[4hys]], [[4hyu]], [[4izy]] – hMAPK8 + JIP1 +inhibitor<br />
 [[2no3]], [[2h96]] – hMAPK8 (mutant)+inhibitor<br />
@@ Line 99: / Line 112: @@
 ===MAPK10===
-[[3kvx]], [[3fv8]], [[2waj]], [[3fi2]], [[3fi3]], [[3da6]], [[2zdt]], [[2zdu]], [[3cgf]], [[3cgo]], [[2r9s]], [[2o0u]], [[2o2u]], [[2exc]], [[2b1p]], [[1pmn]], [[1pmq]], [[1pmu]], [[1pmv]], [[3oy1]], [[2ok1]], [[3ttj]], [[3tti]],  – hMAPK10+inhibitor<br />
+[[3kvx]], [[3fv8]], [[2waj]], [[3fi2]], [[3fi3]], [[3da6]], [[2zdt]], [[2zdu]], [[3cgf]], [[3cgo]], [[2r9s]], [[2o0u]], [[2o2u]], [[2exc]], [[2b1p]], [[1pmn]], [[1pmq]], [[1pmu]], [[1pmv]], [[3oy1]], [[2ok1]], [[3ttj]], [[3tti]], [[3rtp]], [[3v6r]], [[3v6s]] – hMAPK10+inhibitor<br />
 [[3ptg]], [[4h39]] - hMAPK10 catalytic domain + JIP1 peptide <br />
 [[4h36]] – hMAPK10 catalytic domain + ATF2 peptide<br />
@@ Line 113: / Line 126: @@
 ===MAPK13===
-[[3coi]] – hMAPK13<br />
+[[3coi]], [[4exu]] – hMAPK13<br />
+[[4eyj]], [[4eym]] - hMAPK13 +inhibitor<br />
 ===MAPK14===
-[[3mgy]], [[3mh0]], [[3mh1]], [[3mh2]], [[3mh3]], [[3hvc]], [[3npq]], [[1wbo]], [[1r39]], [[2npq]] – hMAPK14<br />
+[[3mgy]], [[3mh0]], [[3mh1]], [[3mh2]], [[3mh3]], [[3hvc]], [[3npq]], [[1wbo]], [[1r39]], [[2npq]], [[1wfc]], [[1cm8]] – hMAPK14<br />
-[[3od6]], [[3ody]], [[3odz]], [[3oef]], [[3p4k]], [[2fsl]], [[2fsm]], [[2fso]], [[2fst]], [[1r3c]] – hMAPK14 (mutant)<br />
+[[2lgc]] – hMAPK14 – NMR<br />
-[[3new]], [[3ocg]], [[3mvl]], [[3mvm]], [[3nnu]], [[3nnv]], [[3nnw]], [[3nnx]], [[3nww]], [[3mpt]], [[3lhj]], [[3huc]], [[3itz]], [[3l8x]], [[3kf7]], [[3fi4]], [[3fkl]], [[3fkn]], [[3fko]], [[3fl4]], [[3fln]], [[3flq]], [[3fls]], [[3flw]], [[3fly]], [[3flz]], [[3fmh]], [[3fmj]], [[3fmk]], [[3fml]], [[3flm]], [[3fln]], [[3fsf]], [[3fsk]], [[3kq7]], [[3iph]], [[3hv4]], [[3hv5]], [[3hv6]], [[3hv7]], [[3k3i]], [[3hec]], [[3heg]], [[3gi3]], [[3hp2]], [[3hp5]], [[3hrb]], [[3ha8]], [[3gfe]], [[3hl7]], [[3hll]], [[3gcu]], [[3fc1]], [[3dt1]], [[3e92]], [[3e93]], [[3d7z]], [[3d83]], [[3ctq]], [[2puu]], [[3bx5]], [[3c5u]], [[2zaz]], [[2zb0]], [[2zb1]], [[2qd9]], [[2ewa]], [[2gfs]], [[2baj]], [[2bak]], [[2bal]], [[2baq]], [[1zyj]], [[1wbn]], [[1wbs]], [[1wbt]], [[1wbv]], [[1wbw]], [[1zz2]], [[1zzl]], [[1yqj]], [[1w7h]], [[1w82]], [[1w83]], [[1w84]], [[1oz1]], [[1ouk]], [[1ouy]], [[1m7q]], [[1kv1]], [[1kv2]], [[1di9]], [[2rg5]], [[2rg6]], [[3bv3]], [[3bv2]], [[3fmm]], [[3fmn]], [[3lfa]], [[3mw1]], [[3pg3]], [[3roc]] - hMAPK14+inhibitor<br />
+[[3od6]], [[3ody]], [[3odz]], [[3oef]], [[3p4k]], [[2fsl]], [[2fsm]], [[2fso]], [[2fst]], [[1r3c]], [[4e5a]], [[4geo]] – hMAPK14 (mutant)<br />
-[[3o8t]], [[3mpa]], [[3obg]], [[3o8u]], [[3o8p]], [[3obj]], [[3oc1]], [[3hub]], [[3l8s]], [[3hv3]], [[3iw5]], [[3iw6]], [[3iw7]], [[3iw8]], [[3k3j]], [[3gc7]], [[3gcp]], [[3gcq]], [[3gcs]], [[3gcv]], [[3ds6]], [[2i0h]], [[1ove]], [[3lfb]], [[3lfc]], [[3lfd]], [[3lfe]], [[3lff]] - hMAPK14 (mutant)+inhibitor<br />
+[[3new]], [[3ocg]], [[3mvl]], [[3mvm]], [[3nnu]], [[3nnv]], [[3nnw]], [[3nnx]], [[3nww]], [[3mpt]], [[3lhj]], [[3huc]], [[3itz]], [[3l8x]], [[3kf7]], [[3fi4]], [[3fkl]], [[3fkn]], [[3fko]], [[3fl4]], [[3fln]], [[3flq]], [[3fls]], [[3flw]], [[3fly]], [[3flz]], [[3fmh]], [[3fmj]], [[3fmk]], [[3fml]], [[3flm]], [[3fln]], [[3fsf]], [[3fsk]], [[3kq7]], [[3iph]], [[3hv4]], [[3hv5]], [[3hv6]], [[3hv7]], [[3k3i]], [[3hec]], [[3heg]], [[3gi3]], [[3hp2]], [[3hp5]], [[3hrb]], [[3ha8]], [[3gfe]], [[3hl7]], [[3hll]], [[3gcu]], [[3fc1]], [[3dt1]], [[3e92]], [[3e93]], [[3d7z]], [[3d83]], [[3ctq]], [[2puu]], [[3bx5]], [[3c5u]], [[2zaz]], [[2zb0]], [[2zb1]], [[2qd9]], [[2ewa]], [[2gfs]], [[2baj]], [[2bak]], [[2bal]], [[2baq]], [[1zyj]], [[1wbn]], [[1wbs]], [[1wbt]], [[1wbv]], [[1wbw]], [[1zz2]], [[1zzl]], [[1yqj]], [[1w7h]], [[1w82]], [[1w83]], [[1w84]], [[1oz1]], [[1ouk]], [[1ouy]], [[1m7q]], [[1kv1]], [[1kv2]], [[1di9]], [[2rg5]], [[2rg6]], [[3bv3]], [[3bv2]], [[3fmm]], [[3fmn]], [[3lfa]], [[3mw1]], [[3pg3]], [[3roc]] ,[[2yis]], [[2yiw]], [[2yix]], [[3qud]], [[3que]], [[3rin]], [[3s3i]], [[3s4q]], [[3u8w]], [[3uvp]], [[3uvq]], [[3uvr]], [[3zs5]], [[3zsg]], [[3zsh]], [[3zsi]], [[3zya]], [[4a9y]], [[4aa0]], [[4aa4]], [[4aa5]], [[4aac]], [[4dli]], [[4dlj]], [[4e5b]], [[4eh2]], [[4eh3]], [[4eh4]], [[4eh5]], [[4eh6]], [[4eh7]], [[4eh8]], [[4eh9]], [[4ehv]], [[4ewq]], [[4f9w]], [[4f9y]], [[4fa2]], [[4kin]], [[4kip]], [[4kiq]], [[4l8m]] - hMAPK14+inhibitor<br />
+[[4e6a]], [[4e6c]], [[4e8a]] - hMAPK14+ lipid<br />
+[[3o8t]], [[3mpa]], [[3obg]], [[3o8u]], [[3o8p]], [[3obj]], [[3oc1]], [[3hub]], [[3l8s]], [[3hv3]], [[3iw5]], [[3iw6]], [[3iw7]], [[3iw8]], [[3k3j]], [[3gc7]], [[3gcp]], [[3gcq]], [[3gcs]], [[3gcv]], [[3ds6]], [[2i0h]], [[1ove]], [[3lfb]], [[3lfc]], [[3lfd]], [[3lfe]], [[3lff]], [[1bl6]], [[1bl7]], [[1bmk]], [[1a9u]], [[1ian]] - hMAPK14 (mutant)+inhibitor<br />
+[[2y8o]] – hMAPK14 (mutant) + dual specificity MAP2K peptide<br />
+[[4ka3]], [[4loo]], [[4lop]], [[4loq]] – hMAPK14 + docking peptide<br />
+[[3tg1]] – hMAPK14 + MAPK phosphatase 5<br />
 [[2gtn]], [[2gtm]], [[3p5k]], [[3p78]], [[3p79]], [[3p7a]], [[3p7b]], [[3p7c]] - mMAPK14+inhibitor<br />
 [[2ghm]], [[2ghl]], [[1ywr]] - mMAPK14 (mutant)+inhibitor<br />
 [[3py3]] - mMAPK14 phosphorylated<br />
-[[1yw2]] - mMAPK14 (mutant)<br />
+[[1yw2]], [[1p38]] - mMAPK14 (mutant)<br />
 [[1lew]] - mMAPK14+MEF2A<br />
 [[1lez]] - mMAPK14+MKK3B<br />
-===MAPK p38===
-[[1wfc]] - hMAPK p38<br />
-[[1bl6]], [[1bl7]], [[1bmk]], [[1a9u]], [[1ian]] – hMAPK p38 (mutant)+inhibitor<br />
-[[1p38]] - mMAPK p38 (mutant) - mouse<br />
 ===MAPK FUSS===
@@ Line 142: / Line 156: @@
 [[2b9j]] - yMAPK FUSS (mutant)+FAR1 peptide<br />
-[[3rp9]] – MAPK – ''Toxoplasma gondii''
+[[3rp9]] – MAPK – ''Toxoplasma gondii''<br />
+[[3uib]] – MAPK + inhibitor – ''Leishmania major''<br />
 [[Category:Topic Page]]