2q3c
From Proteopedia
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{{STRUCTURE_2q3c| PDB=2q3c | SCENE= }} | {{STRUCTURE_2q3c| PDB=2q3c | SCENE= }} | ||
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===2.1 A Resolution Crystal Structure of O-Acetylserine Sulfhydrylase (OASS) Holoenzyme From MYCOBACTERIUM TUBERCULOSIS in Complex with the Inhibitory Peptide DFSI=== | ===2.1 A Resolution Crystal Structure of O-Acetylserine Sulfhydrylase (OASS) Holoenzyme From MYCOBACTERIUM TUBERCULOSIS in Complex with the Inhibitory Peptide DFSI=== | ||
| + | {{ABSTRACT_PUBMED_17567578}} | ||
| - | + | ==Function== | |
| + | [[http://www.uniprot.org/uniprot/CYSK_MYCTU CYSK_MYCTU]] Catalyzes the conversion of O-acetylserine (OAS) to cysteine through the elimination of acetate and addition of hydrogen sulfide. | ||
==About this Structure== | ==About this Structure== | ||
| - | [[2q3c]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/ | + | [[2q3c]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_tuberculosis"_(zopf_1883)_klein_1884 "bacillus tuberculosis" (zopf 1883) klein 1884]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Q3C OCA]. |
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID:017567578</ref><references group="xtra"/> | + | <ref group="xtra">PMID:017567578</ref><references group="xtra"/><references/> |
[[Category: Cysteine synthase]] | [[Category: Cysteine synthase]] | ||
| - | [[Category: Mycobacterium tuberculosis]] | ||
[[Category: Schneider, G.]] | [[Category: Schneider, G.]] | ||
[[Category: Schnell, R.]] | [[Category: Schnell, R.]] | ||
Revision as of 07:35, 2 April 2014
Contents |
2.1 A Resolution Crystal Structure of O-Acetylserine Sulfhydrylase (OASS) Holoenzyme From MYCOBACTERIUM TUBERCULOSIS in Complex with the Inhibitory Peptide DFSI
Template:ABSTRACT PUBMED 17567578
Function
[CYSK_MYCTU] Catalyzes the conversion of O-acetylserine (OAS) to cysteine through the elimination of acetate and addition of hydrogen sulfide.
About this Structure
2q3c is a 2 chain structure with sequence from "bacillus_tuberculosis"_(zopf_1883)_klein_1884 "bacillus tuberculosis" (zopf 1883) klein 1884. Full crystallographic information is available from OCA.
Reference
- Schnell R, Oehlmann W, Singh M, Schneider G. Structural insights into catalysis and inhibition of O-acetylserine sulfhydrylase from Mycobacterium tuberculosis. Crystal structures of the enzyme alpha-aminoacrylate intermediate and an enzyme-inhibitor complex. J Biol Chem. 2007 Aug 10;282(32):23473-81. Epub 2007 Jun 13. PMID:17567578 doi:10.1074/jbc.M703518200
