4lhh

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-	'''Unreleased structure'''	+	{{STRUCTURE_4lhh| PDB=4lhh | SCENE= }}
		+	===Endothiapepsin in complex with 2mM acylhydrazone inhibitor===
		+	{{ABSTRACT_PUBMED_24532096}}
-	The entry 4lhh is ON HOLD until Paper Publication	+	==About this Structure==
		+	[[4lhh]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Cryphonectria_parasitica Cryphonectria parasitica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LHH OCA].
-	Authors: Radeva, N., Heine, A., Klebe, G.	+	==Reference==
-		+	<ref group="xtra">PMID:024532096</ref><references group="xtra"/><references/>
-	Description: Endothiapepsin in complex with 2mM acylhydrazone inhibitor	+	[[Category: Cryphonectria parasitica]]
		+	[[Category: Endothiapepsin]]
		+	[[Category: Heine, A.]]
		+	[[Category: Klebe, G.]]
		+	[[Category: Radeva, N.]]
		+	[[Category: Aspartic protease]]
		+	[[Category: Hydrolase]]
		+	[[Category: Hydrolase-hydrolase inhibitor complex]]

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Revision as of 09:00, 2 April 2014

Template:STRUCTURE 4lhh

Endothiapepsin in complex with 2mM acylhydrazone inhibitor

Template:ABSTRACT PUBMED 24532096

About this Structure

4lhh is a 1 chain structure with sequence from Cryphonectria parasitica. Full crystallographic information is available from OCA.

Reference

• Mondal M, Radeva N, Koster H, Park A, Potamitis C, Zervou M, Klebe G, Hirsch AK. Structure-based design of inhibitors of the aspartic protease endothiapepsin by exploiting dynamic combinatorial chemistry. Angew Chem Int Ed Engl. 2014 Mar 17;53(12):3259-63. doi: 10.1002/anie.201309682. , Epub 2014 Feb 14. PMID:24532096 doi:http://dx.doi.org/10.1002/anie.201309682