4k10

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'''Unreleased structure'''
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{{STRUCTURE_4k10| PDB=4k10 | SCENE= }}
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===Crystal Structure of Leshmaniasis major Farnesyl diphosphate synthase in complex with 3-FLUORO-1-(2-HYDROXY-2,2-DIPHOSPHONOETHYL)PYRIDINIUM and Mg2+===
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{{ABSTRACT_PUBMED_24598749}}
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The entry 4k10 is ON HOLD until Paper Publication
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==About this Structure==
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[[4k10]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4K10 OCA].
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Authors: Aripirala, S., Gabelli, S., Amzel, L.M.
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==Reference==
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<ref group="xtra">PMID:024598749</ref><references group="xtra"/><references/>
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Description: Crystal Structure of Leshmaniasis major Farnesyl diphosphate synthase in complex with 3-FLUORO-1-(2-HYDROXY-2,2-DIPHOSPHONOETHYL)PYRIDINIUM and Mg2+
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[[Category: Amzel, L M.]]
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[[Category: Aripirala, S.]]
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[[Category: Gabelli, S.]]
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[[Category: Farnesyl diphosphate synthase]]
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[[Category: Farnesyl pyrophosphate synthase]]
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[[Category: Fpp]]
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[[Category: Geranyl transferase]]
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[[Category: Transferase-transferase inhibitor complex]]

Revision as of 09:25, 2 April 2014

Template:STRUCTURE 4k10

Crystal Structure of Leshmaniasis major Farnesyl diphosphate synthase in complex with 3-FLUORO-1-(2-HYDROXY-2,2-DIPHOSPHONOETHYL)PYRIDINIUM and Mg2+

Template:ABSTRACT PUBMED 24598749

About this Structure

4k10 is a 4 chain structure. Full crystallographic information is available from OCA.

Reference

  • Aripirala S, Gonzalez-Pacanowska D, Oldfield E, Kaiser M, Amzel LM, Gabelli SB. Structural and thermodynamic basis of the inhibition of Leishmania major farnesyl diphosphate synthase by nitrogen-containing bisphosphonates. Acta Crystallogr D Biol Crystallogr. 2014 Mar;70(Pt 3):802-10. doi:, 10.1107/S1399004713033221. Epub 2014 Feb 22. PMID:24598749 doi:http://dx.doi.org/10.1107/S1399004713033221

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