Phenylethanolamine N-methyltransferase
From Proteopedia
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== 3D Structures of Phenylethanolamine N-methyltransferase == | == 3D Structures of Phenylethanolamine N-methyltransferase == | ||
| - | + | Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} | |
[[3kpj]] – hPNMT+AdoHcy – human<br /> | [[3kpj]] – hPNMT+AdoHcy – human<br /> | ||
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[[3hcd]] - hPNMT+AdoHcy+noradrenaline<br /> | [[3hcd]] - hPNMT+AdoHcy+noradrenaline<br /> | ||
[[2g72]] - hPNMT+AdoMet+ligand<br /> | [[2g72]] - hPNMT+AdoMet+ligand<br /> | ||
| + | [[2opb]] - hPNMT+AdoMet + inhibitor<br /> | ||
[[2an3]] - hPNMT+AdoHcy+substrate analog<br /> | [[2an3]] - hPNMT+AdoHcy+substrate analog<br /> | ||
[[2an4]] - hPNMT+AdoHcy+octopamine<br /> | [[2an4]] - hPNMT+AdoHcy+octopamine<br /> | ||
Revision as of 10:25, 3 April 2014
Phenylethanolamine N-methyltransferase (PNMT) catalyzes the conversion of norepinephrine (noradrenaline) to epinephrine (adrenaline). This is the last step in the conversion of tyrosine to adrenaline. S-adenosyl-L-homocysteine (AdoHcy) by itself or with other ligands are inhibitors of PNMT. The images at the left and at the right correspond to one representative PNMT, i.e. the crystal structure of Phenylethanolamine N-methyltransferase (3kpj).
3D Structures of Phenylethanolamine N-methyltransferase
Updated on 03-April-2014
3kpj – hPNMT+AdoHcy – human
3kpu, 3kpv, 3kpw, 3kpy, 3kqm, 3kqo, 3kqp, 3kqq, 3kqs, 3kqt, 3kqv, 3kqw, 3kqy, 3kr0, 3kr1, 3kr2, 3hcb, 3hcc, 3hcf, 2ony, 2g70, 2g71, 2g8n, 2an5, 1yz3, 1n7i, 1n7j, 1hnn - hPNMT+AdoHcy+ligand
3hca, 3hce, 2obf, 2onz, 2obp - hPNMT (mutant)+AdoHcy+ligand
3hcd - hPNMT+AdoHcy+noradrenaline
2g72 - hPNMT+AdoMet+ligand
2opb - hPNMT+AdoMet + inhibitor
2an3 - hPNMT+AdoHcy+substrate analog
2an4 - hPNMT+AdoHcy+octopamine
4dm3 - hPNMT+AdoHcy + resorcinol + imidazole
