1p0z

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[[Image:1p0z.png|left|200px]]
 
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{{STRUCTURE_1p0z| PDB=1p0z | SCENE= }}
{{STRUCTURE_1p0z| PDB=1p0z | SCENE= }}
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===Sensor Kinase CitA binding domain===
===Sensor Kinase CitA binding domain===
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{{ABSTRACT_PUBMED_12867417}}
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{{ABSTRACT_PUBMED_12867417}}
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==Function==
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[[http://www.uniprot.org/uniprot/CITA_KLEPN CITA_KLEPN]] Member of the two-component regulatory system CitA/CitB. Probably activates CitB by phosphorylation. The periplasmic domain binds H-citrate(2-), which is essential for induction of the citrate-fermentation genes.<ref>PMID:10447894</ref>
==About this Structure==
==About this Structure==
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[[1p0z]] is a 10 chain structure with sequence from [http://en.wikipedia.org/wiki/Klebsiella_pneumoniae Klebsiella pneumoniae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1P0Z OCA].
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[[1p0z]] is a 10 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_pneumoniae"_(schroeter_1886)_flugge_1886 "bacillus pneumoniae" (schroeter 1886) flugge 1886]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1P0Z OCA].
==Reference==
==Reference==
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<ref group="xtra">PMID:012867417</ref><references group="xtra"/>
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<ref group="xtra">PMID:012867417</ref><references group="xtra"/><references/>
[[Category: Histidine kinase]]
[[Category: Histidine kinase]]
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[[Category: Klebsiella pneumoniae]]
 
[[Category: Bott, M.]]
[[Category: Bott, M.]]
[[Category: Gerharz, T.]]
[[Category: Gerharz, T.]]

Revision as of 04:31, 9 April 2014

Template:STRUCTURE 1p0z

Contents

Sensor Kinase CitA binding domain

Template:ABSTRACT PUBMED 12867417

Function

[CITA_KLEPN] Member of the two-component regulatory system CitA/CitB. Probably activates CitB by phosphorylation. The periplasmic domain binds H-citrate(2-), which is essential for induction of the citrate-fermentation genes.[1]

About this Structure

1p0z is a 10 chain structure with sequence from "bacillus_pneumoniae"_(schroeter_1886)_flugge_1886 "bacillus pneumoniae" (schroeter 1886) flugge 1886. Full crystallographic information is available from OCA.

Reference

  • Reinelt S, Hofmann E, Gerharz T, Bott M, Madden DR. The structure of the periplasmic ligand-binding domain of the sensor kinase CitA reveals the first extracellular PAS domain. J Biol Chem. 2003 Oct 3;278(40):39189-96. Epub 2003 Jul 16. PMID:12867417 doi:10.1074/jbc.M305864200
  1. Kaspar S, Perozzo R, Reinelt S, Meyer M, Pfister K, Scapozza L, Bott M. The periplasmic domain of the histidine autokinase CitA functions as a highly specific citrate receptor. Mol Microbiol. 1999 Aug;33(4):858-72. PMID:10447894

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